The intertwined physics of active chemical reactions and phase separation
D Zwicker - Current Opinion in Colloid & Interface Science, 2022 - Elsevier
Phase separation is the thermodynamic process that explains how droplets form in
multicomponent fluids. These droplets can provide controlled compartments to localize …
multicomponent fluids. These droplets can provide controlled compartments to localize …
Putting the squeeze on phase separation
Phase separation is a ubiquitous process and finds applications in a variety of biological,
organic, and inorganic systems. Nature has evolved the ability to control phase separation to …
organic, and inorganic systems. Nature has evolved the ability to control phase separation to …
[HTML][HTML] Non-specific adhesive forces between filaments and membraneless organelles
TJ Böddeker, KA Rosowski, D Berchtold… - Nature physics, 2022 - nature.com
Many membraneless organelles are liquid-like domains that form inside the active,
viscoelastic environment of living cells through phase separation. To investigate the …
viscoelastic environment of living cells through phase separation. To investigate the …
Morphogenesis and cell ordering in confined bacterial biofilms
Biofilms are aggregates of bacterial cells surrounded by an extracellular matrix. Much
progress has been made in studying biofilm growth on solid substrates; however, little is …
progress has been made in studying biofilm growth on solid substrates; however, little is …
Mechanical frustration of phase separation in the cell nucleus by chromatin
Liquid-liquid phase separation is a fundamental mechanism underlying subcellular
organization. Motivated by the striking observation that optogenetically generated droplets in …
organization. Motivated by the striking observation that optogenetically generated droplets in …
Modeling elastically mediated liquid-liquid phase separation
We propose a continuum theory of the liquid-liquid phase separation in an elastic network,
where phase-separated microscopic droplets rich in one fluid component can form as an …
where phase-separated microscopic droplets rich in one fluid component can form as an …
Liquid demixing in elastic networks: Cavitation, permeation, or size selection?
In cells, phase-separated liquid condensates interact mechanically with surrounding elastic
networks such as chromatin and cytoskeleton. By considering the trade-offs between elastic …
networks such as chromatin and cytoskeleton. By considering the trade-offs between elastic …
Cavitation controls droplet sizes in elastic media
E Vidal-Henriquez, D Zwicker - Proceedings of the National …, 2021 - National Acad Sciences
Biological cells use droplets to separate components and spatially control their interior.
Experiments demonstrate that the complex, crowded cellular environment affects the droplet …
Experiments demonstrate that the complex, crowded cellular environment affects the droplet …
Designing the morphology of separated phases in multicomponent liquid mixtures
Phase separation of multicomponent liquid mixtures plays an integral part in many
processes ranging from industry to cellular biology. In many cases the morphology of …
processes ranging from industry to cellular biology. In many cases the morphology of …
Heterogeneous elasticity drives ripening and controls bursting kinetics of transcriptional condensates
Many biomolecular condensates, including transcriptional condensates, are formed in
elastic mediums. In this work, we study the nonequilibrium condensate dynamics in a …
elastic mediums. In this work, we study the nonequilibrium condensate dynamics in a …