Effectiveness of Drug Repurposing and Natural Products Against SARS-CoV-2: A Comprehensive Review
Abstract The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a
betacoronavirus responsible for the COVID-19 pandemic, causing respiratory disorders, and …
betacoronavirus responsible for the COVID-19 pandemic, causing respiratory disorders, and …
Artemisinins in combating viral infections like SARS-CoV-2, inflammation and cancers and options to meet increased global demand
K Farmanpour-Kalalagh… - Frontiers in Plant …, 2022 - frontiersin.org
Artemisinin is a natural bioactive sesquiterpene lactone containing an unusual
endoperoxide 1, 2, 4-trioxane ring. It is derived from the herbal medicinal plant Artemisia …
endoperoxide 1, 2, 4-trioxane ring. It is derived from the herbal medicinal plant Artemisia …
Combined computational approaches for developing new anti-Alzheimer drug candidates: 3D-QSAR, molecular docking and molecular dynamics studies of …
Butyrylcholinesterase is an acetylcholine-degrading enzyme involved in the memorization
process, which is becoming an interesting target for the symptomatic treatment of …
process, which is becoming an interesting target for the symptomatic treatment of …
3D-QSAR, ADME-Tox, and molecular docking of semisynthetic triterpene derivatives as antibacterial and insecticide agents
O Daoui, N Mazoir, M Bakhouch, M Salah… - Structural Chemistry, 2022 - Springer
In the present work, 27 triterpene derivatives have been subjected to 3D-QSAR, ADME-Tox,
and molecular docking for their insecticidal activity. The selected derivatives are previously …
and molecular docking for their insecticidal activity. The selected derivatives are previously …
Structure‐based Virtual Screening, ADMET analysis, and molecular dynamics simulation of Moroccan natural compounds as candidates α‐amylase inhibitors
Current treatments for diabetes mellitus are ineffective, as evidenced by the rise in diabetes
cases. This has forced researchers to develop novel chemicals as drugs to block the …
cases. This has forced researchers to develop novel chemicals as drugs to block the …
In silico investigation of phytoconstituents from Cameroonian medicinal plants towards COVID-19 treatment
In silico studies performed on the metabolites of four Cameroonian medicinal plants with a
view to propose potential molecules to fight against COVID-19 were carried out. At first …
view to propose potential molecules to fight against COVID-19 were carried out. At first …
Dependence on linkers' flexibility designed for benzenesulfonamides targeting discovery of novel hCA IX inhibitors as potent anticancer agents
Herein we reported the design and synthesis of two series comprising twenty-two
benzenesulfonamides that integrate the s-triazine moiety. Target compounds successfully …
benzenesulfonamides that integrate the s-triazine moiety. Target compounds successfully …
Genotoxic effects and mitosis aberrations of chromium (VI) on root cells of Vicia faba and its molecular docking analysis
Like other heavy metals, Cr (VI) is a powerful carcinogen and mutagen agent. Its toxic effects
on plants are well considered. In order to elucidate its adverse effects, the present work aims …
on plants are well considered. In order to elucidate its adverse effects, the present work aims …
Identification of potential bioactive natural compounds from Indonesian medicinal plants against 3-chymotrypsin-like protease (3CLpro) of SARS-CoV-2: molecular …
WE Prasetyo, H Purnomo, M Sadrini… - Journal of …, 2023 - Taylor & Francis
An outbreak of SARS-CoV-2 (COVID-19) has caused a global health emergency, resulting
in hundreds of millions of infections and millions of deaths globally since December 2019 …
in hundreds of millions of infections and millions of deaths globally since December 2019 …
Computational study of quinoline-based thiadiazole compounds as potential antileishmanial inhibitors
Leishmaniasis is a severe disease caused by protozoan parasites of the genus Leishmania
and it is accountable for sizable morbidity and mortality worldwide. So far, no effective …
and it is accountable for sizable morbidity and mortality worldwide. So far, no effective …