Mechanism of action of ribosomally synthesized and post-translationally modified peptides

C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Enzymatic carbon–sulfur bond formation in natural product biosynthesis

KL Dunbar, DH Scharf, A Litomska… - Chemical …, 2017 - ACS Publications
Sulfur plays a critical role for the development and maintenance of life on earth, which is
reflected by the wealth of primary metabolites, macromolecules, and cofactors bearing this …

Antibacterial activities of bacteriocins: application in foods and pharmaceuticals

SC Yang, CH Lin, CT Sung, JY Fang - Frontiers in microbiology, 2014 - frontiersin.org
Bacteriocins are a kind of ribosomal synthesized antimicrobial peptides produced by
bacteria, which can kill or inhibit bacterial strains closely-related or non-related to produced …

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

PG Arnison, MJ Bibb, G Bierbaum, AA Bowers… - Natural product …, 2013 - pubs.rsc.org
Covering: 1988 to 2012 This review presents recommended nomenclature for the
biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) …

Radical S-Adenosylmethionine Enzymes

JB Broderick, BR Duffus, KS Duschene… - Chemical …, 2014 - ACS Publications
It was once widely held that nearly all reactions in biology were catalyzed via mechanisms
involving paired electron species. Beginning approximately 40 years ago, this paradigm was …

Antimicrobial mechanisms and clinical application prospects of antimicrobial peptides

X Li, S Zuo, B Wang, K Zhang, Y Wang - Molecules, 2022 - mdpi.com
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

Oxidative cyclization in natural product biosynthesis

MC Tang, Y Zou, K Watanabe, CT Walsh… - Chemical …, 2017 - ACS Publications
Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …

Antimicrobial peptides of the genus Bacillus: a new era for antibiotics

CD Sumi, BW Yang, IC Yeo… - Canadian journal of …, 2015 - cdnsciencepub.com
The rapid onset of resistance reduces the efficacy of most conventional antimicrobial drugs
and is a general cause of concern for human well-being. Thus, there is great demand for a …

Antimicrobial Bacillus: Metabolites and Their Mode of Action

C Tran, IE Cock, X Chen, Y Feng - Antibiotics, 2022 - mdpi.com
The agricultural industry utilizes antibiotic growth promoters to promote livestock growth and
health. However, the World Health Organization has raised concerns over the ongoing …

Diversity and applications of Bacillus bacteriocins

H Abriouel, CMAP Franz, NB Omar… - FEMS microbiology …, 2011 - academic.oup.com
Members of the genus Bacillus are known to produce a wide arsenal of antimicrobial
substances, including peptide and lipopeptide antibiotics, and bacteriocins. Many of the …