[HTML][HTML] Consensus Guidance for Monitoring Individuals With Islet Autoantibody–Positive Pre-Stage 3 Type 1 Diabetes
M Phillip, P Achenbach, A Addala… - Diabetes …, 2024 - diabetesjournals.org
Given the proven benefits of screening to reduce diabetic ketoacidosis (DKA) likelihood at
the time of stage 3 type 1 diabetes diagnosis, and emerging availability of therapy to delay …
the time of stage 3 type 1 diabetes diagnosis, and emerging availability of therapy to delay …
Lipid peroxidation linking diabetes and cancer: the importance of 4-hydroxynonenal
M Jaganjac, N Zarkovic - Antioxidants & redox signaling, 2022 - liebertpub.com
Significance: It is commonly believed that diabetes mellitus may be associated with cancer.
Hence, diabetic patients are at higher risk for hepatocellular carcinoma, pancreatic cancer …
Hence, diabetic patients are at higher risk for hepatocellular carcinoma, pancreatic cancer …
[HTML][HTML] Dysregulation of secondary bile acid metabolism precedes islet autoimmunity and type 1 diabetes
The gut microbiota is crucial in the regulation of bile acid (BA) metabolism. However, not
much is known about the regulation of BAs during progression to type 1 diabetes (T1D) …
much is known about the regulation of BAs during progression to type 1 diabetes (T1D) …
[HTML][HTML] Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection
Although the genetic basis and pathogenesis of type 1 diabetes have been studied
extensively, how host responses to environmental factors might contribute to autoantibody …
extensively, how host responses to environmental factors might contribute to autoantibody …
An overview of metabolomics data analysis: current tools and future perspectives
Metabolomics is a study of small molecules in the body and the associated metabolic
pathways and is considered to provide a close link between organism's genotype and …
pathways and is considered to provide a close link between organism's genotype and …
[HTML][HTML] Systems biology approaches to study lipidomes in health and disease
Lipids have many important biological roles, such as energy storage sources, structural
components of plasma membranes and as intermediates in metabolic and signaling …
components of plasma membranes and as intermediates in metabolic and signaling …
[HTML][HTML] Plasma protein biomarkers predict the development of persistent autoantibodies and type 1 diabetes 6 months prior to the onset of autoimmunity
ES Nakayasu, LM Bramer, C Ansong… - Cell Reports …, 2023 - cell.com
Summary Type 1 diabetes (T1D) results from autoimmune destruction of β cells. Insufficient
availability of biomarkers represents a significant gap in understanding the disease cause …
availability of biomarkers represents a significant gap in understanding the disease cause …
Circulating free fatty acid and phospholipid signature predicts early rapid kidney function decline in patients with type 1 diabetes
F Afshinnia, TM Rajendiran, C He, J Byun… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVES Patients with type 1 diabetes (T1D) exhibit modest lipid abnormalities as
measured by traditional metrics. This study aimed to identify lipidomic predictors of rapid …
measured by traditional metrics. This study aimed to identify lipidomic predictors of rapid …
Metabolomics of type 1 and type 2 diabetes: insights into risk prediction and mechanisms
DG Izundegui, M Nayor - Current diabetes reports, 2022 - Springer
Abstract Purpose of Review Metabolomics enables rapid interrogation of widespread
metabolic processes making it well suited for studying diabetes. Here, we review the current …
metabolic processes making it well suited for studying diabetes. Here, we review the current …
[HTML][HTML] Lipidomes in health and disease: Analytical strategies and considerations
F Wei, S Lamichhane, M Orešič… - TrAC Trends in Analytical …, 2019 - Elsevier
Lipidomics is a rapidly-growing field which focuses on global characterization of lipids at
molecular and systems levels. As small changes in the concentrations of lipids may have …
molecular and systems levels. As small changes in the concentrations of lipids may have …