Metformin, one of the oldest oral antidiabetic agents and still recommended by almost all
current guidelines as the first-line treatment for type 2 diabetes mellitus (T2DM), has become …

Metformin (MF), a first-line drug to treat type 2 diabetes mellitus (T2DM), alone and in
combination with other drugs, restores the ovarian function in women with polycystic ovary …

Background Although metformin is increasingly being used in women with type 2 diabetes
during pregnancy, little data exist on the benefits and harms of metformin use on pregnancy …

Introduction This study aimed to investigate if maternal pregnancy exposure to metformin is
associated with increased risk of long-term and short-term adverse outcomes in the child …

Background Gestational diabetes that is not properly controlled with diet has been
commonly treated with insulin. In recent years, several studies have published that …

Importance Increasing use of second-line noninsulin antidiabetic medication (ADM) in
pregnant individuals with type 2 diabetes (T2D) may result in fetal exposure, but their …

Owing to limited drug testing possibilities in pregnant population, the development of
computational algorithms is crucial to predict the fate of drugs in the placental barrier; it …

Aims/hypothesis Metformin is increasingly used to treat gestational diabetes (GDM) and
pregnancies complicated by pregestational type 2 diabetes or polycystic ovary syndrome but …

OBJECTIVE To assess the risk of major congenital malformations with metformin versus
insulin in pregnancies with type 2 diabetes. RESEARCH DESIGN AND METHODS This …

Metformin (MTF) occupies a major and fundamental position in the therapeutic management
of type 2 diabetes mellitus (T2DM). Gender differences in some effects and actions of MTF …