Oxidative Stress and Osteoporosis : JBJS Oxidative Stress and Osteoporosis : JBJS JBJS Journal
Case Connector Reviews JBJS.org Surgical Techniques Open Access JOPA Log in Subscribe …

Reactive oxygen species (ROS) and free radicals are essential for transmission of cell
signals and other physiological functions. However, excessive amounts of ROS can cause …

ROS are highly reactive molecules which consist of a number of diverse chemical species,
including radical and non-radical oxygen species. Oxidative stress occurs as a result of an …

Bone homeostasis involves bone formation and bone resorption, which are processes that
maintain skeletal health. Oxidative stress is an independent risk factor, causing the …

Osteoporosis is a systemic metabolic bone disease characterized by a reduction in bone
mass, bone quality, and microarchitectural deterioration. An imbalance in bone remodeling …

Accumulating evidence indicates that intracellular reactive oxygen species (ROS)
production is highly involved in bone homeostasis by intervening osteoclast or osteoblast …

Osteoclasts are cells derived from bone marrow macrophages and are important in
regulating bone resorption during bone homeostasis. Understanding what drives osteoclast …

Bone remodeling is a tightly controlled mechanism in which osteoblasts (OB), the cells
responsible for bone formation, osteoclasts (OC), the cells specialized for bone resorption …

Melatonin is the primary circadian output signal from the brain and is mainly synthesized in
pinealocytes. The rhythm and secretion of melatonin are under the control of an …

Magnesium (Mg)-based biometal attracts clinical applications due to its biodegradability and
beneficial biological effects on tissue regeneration, especially in orthopaedics, yet the …