The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Microbiota-derived metabolites as drivers of gut–brain communication

H Ahmed, Q Leyrolle, V Koistinen, O Kärkkäinen… - Gut …, 2022 - Taylor & Francis
Alterations in the gut microbiota composition have been associated with a range of
neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The gut microbes …

Gut firmicutes: Relationship with dietary fiber and role in host homeostasis

Y Sun, S Zhang, Q Nie, H He, H Tan… - Critical reviews in …, 2023 - Taylor & Francis
Firmicutes and Bacteroidetes are the predominant bacterial phyla colonizing the healthy
human gut. Accumulating evidence suggests that dietary fiber plays a crucial role in host …

Gut microbial molecules in behavioural and neurodegenerative conditions

BD Needham, R Kaddurah-Daouk… - Nature Reviews …, 2020 - nature.com
Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …

The influence of the microbiome on respiratory health

TP Wypych, LC Wickramasinghe, BJ Marsland - Nature immunology, 2019 - nature.com
The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …

Spermidine in health and disease

F Madeo, T Eisenberg, F Pietrocola, G Kroemer - Science, 2018 - science.org
BACKGROUND As the world population ages, chronic diseases such as diabetes,
cardiovascular disease, cancer, and neurodegeneration become ever more prevalent …

[HTML][HTML] Mouse microbiota models: comparing germ-free mice and antibiotics treatment as tools for modifying gut bacteria

EA Kennedy, KY King, MT Baldridge - Frontiers in physiology, 2018 - frontiersin.org
As the intestinal microbiota has become better appreciated as necessary for maintenance of
physiologic homeostasis and also as a modulator of disease processes, there has been a …

Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon

A Nakamura, S Kurihara, D Takahashi… - Nature …, 2021 - nature.com
Intestinal microbiota-derived metabolites have biological importance for the host.
Polyamines, such as putrescine and spermidine, are produced by the intestinal microbiota …

[HTML][HTML] Metabolite interactions between host and microbiota during health and disease: Which feeds the other?

Y Zhang, R Chen, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

The microbial metabolite desaminotyrosine protects from influenza through type I interferon

AL Steed, GP Christophi, GE Kaiko, L Sun… - Science, 2017 - science.org
The microbiota is known to modulate the host response to influenza infection through as-yet-
unclear mechanisms. We hypothesized that components of the microbiota exert effects …