Recent progress in biological activities of indole and indole alkaloids

TP Singh, OM Singh - Mini reviews in medicinal chemistry, 2018 - ingentaconnect.com
The indole scaffold is found in a wide range of bioactive heterocycles and natural products.
Moreover, the indole moiety is considered as the active principle in several alkaloids such …

Modeling infectious disease dynamics in the complex landscape of global health

H Heesterbeek, RM Anderson, V Andreasen, S Bansal… - Science, 2015 - science.org
BACKGROUND Despite many notable successes in prevention and control, infectious
diseases remain an enormous threat to human and animal health. The ecological and …

Risk factors for tuberculosis

P Narasimhan, J Wood, CR MacIntyre… - Pulmonary …, 2013 - Wiley Online Library
The risk of progression from exposure to the tuberculosis bacilli to the development of active
disease is a two‐stage process governed by both exogenous and endogenous risk factors …

Daylight-driven rechargeable antibacterial and antiviral nanofibrous membranes for bioprotective applications

Y Si, Z Zhang, W Wu, Q Fu, K Huang, N Nitin… - Science …, 2018 - science.org
Emerging infectious diseases (EIDs) are a significant burden on global economies and
public health. Most present personal protective equipment used to prevent EID transmission …

Mycobacterium tuberculosis: success through dormancy

M Gengenbacher, SHE Kaufmann - FEMS microbiology reviews, 2012 - academic.oup.com
Tuberculosis (TB) remains a major health threat, killing nearly 2 million individuals around
this globe, annually. The only vaccine, developed almost a century ago, provides limited …

The challenge of new drug discovery for tuberculosis

A Koul, E Arnoult, N Lounis, J Guillemont, K Andries - Nature, 2011 - nature.com
Tuberculosis (TB) is more prevalent in the world today than at any other time in human
history. Mycobacterium tuberculosis, the pathogen responsible for TB, uses diverse …

HIV and tuberculosis: a deadly human syndemic

CK Kwan, JD Ernst - Clinical microbiology reviews, 2011 - Am Soc Microbiol
SUMMARY A syndemic is defined as the convergence of two or more diseases that act
synergistically to magnify the burden of disease. The intersection and syndemic interaction …

Whole Genome Sequencing versus Traditional Genotyping for Investigation of a Mycobacterium tuberculosis Outbreak: A Longitudinal Molecular Epidemiological …

A Roetzer, R Diel, TA Kohl, C Rückert, U Nübel… - PLoS …, 2013 - journals.plos.org
Background Understanding Mycobacterium tuberculosis (Mtb) transmission is essential to
guide efficient tuberculosis control strategies. Traditional strain typing lacks sufficient …

Minisci reactions: Versatile CH-functionalizations for medicinal chemists

MAJ Duncton - MedChemComm, 2011 - pubs.rsc.org
The addition of a radical to a heteroaromatic base is commonly referred to as a Minsici
reaction. Such reactions constitute a broad-set of selective CH-functionalization processes …

Delays in diagnosis and treatment of pulmonary tuberculosis in India: a systematic review

CT Sreeramareddy, ZZ Qin… - … of Tuberculosis and …, 2014 - ingentaconnect.com
OBJECTIVE: To systematically review Indian literature on delays in tuberculosis (TB)
diagnosis and treatment. METHODS: We searched multiple sources for studies on delays in …