Estrogen effects on cognitive and synaptic health over the lifecourse
Estrogen facilitates higher cognitive functions by exerting effects on brain regions such as
the prefrontal cortex and hippocampus. Estrogen induces spinogenesis and synaptogenesis …
the prefrontal cortex and hippocampus. Estrogen induces spinogenesis and synaptogenesis …
Dendritic spines: the locus of structural and functional plasticity
C Sala, M Segal - Physiological reviews, 2014 - journals.physiology.org
The introduction of high-resolution time lapse imaging and molecular biological tools has
changed dramatically the rate of progress towards the understanding of the complex …
changed dramatically the rate of progress towards the understanding of the complex …
[HTML][HTML] Structural plasticity of the hippocampus in response to estrogens in female rodents
It is well established that estrogens affect neuroplasticity in a number of brain regions. In
particular, estrogens modulate and mediate spine and synapse formation as well as …
particular, estrogens modulate and mediate spine and synapse formation as well as …
Maternal exposure to polystyrene nanoplastics causes brain abnormalities in progeny
B Jeong, JY Baek, J Koo, S Park, YK Ryu… - Journal of Hazardous …, 2022 - Elsevier
As global plastic production continues to grow, microplastics released from a massive
quantity of plastic wastes have become a critical environmental concern. These microplastic …
quantity of plastic wastes have become a critical environmental concern. These microplastic …
Sex differences in the brain: Implications for behavioral and biomedical research
Biological differences between males and females are found at multiple levels. However,
females have too often been under-represented in behavioral neuroscience research, which …
females have too often been under-represented in behavioral neuroscience research, which …
Sex steroid hormones matter for learning and memory: estrogenic regulation of hippocampal function in male and female rodents
Ample evidence has demonstrated that sex steroid hormones, such as the potent estrogen
17β-estradiol (E2), affect hippocampal morphology, plasticity, and memory in male and …
17β-estradiol (E2), affect hippocampal morphology, plasticity, and memory in male and …
Dendritic spine changes associated with normal aging
Given the rapid rate of population aging and the increased incidence of cognitive decline
and neurodegenerative diseases with advanced age, it is important to ascertain the …
and neurodegenerative diseases with advanced age, it is important to ascertain the …
Sex differences in hippocampal function
Sex differences in the function of the hippocampus have been observed in numerous
mammalian species. However, the magnitude, extent, and specificity of these differences are …
mammalian species. However, the magnitude, extent, and specificity of these differences are …
Why estrogens matter for behavior and brain health
Abstract The National Institutes of Health (NIH) has required the inclusion of women in
clinical studies since 1993, which has enhanced our understanding of how biological sex …
clinical studies since 1993, which has enhanced our understanding of how biological sex …
Uncovering the mechanisms of estrogen effects on hippocampal function
JL Spencer, EM Waters, RD Romeo, GE Wood… - Frontiers in …, 2008 - Elsevier
Estrogens have direct effects on the brain areas controlling cognition. One of the most
studied of these regions is the dorsal hippocampal formation, which governs the formation of …
studied of these regions is the dorsal hippocampal formation, which governs the formation of …