Late adverse effects and quality of life in survivors of testicular germ cell tumour

M Chovanec, J Lauritsen, M Bandak, C Oing… - Nature Reviews …, 2021 - nature.com
Abstract Currently,~ 95% of patients with testicular germ cell tumour (TGCT) are cured,
resulting in an increasing number of TGCT survivors. Although cured, these men face …

Testicular cancer survivorship

C Fung, PC Dinh, SD Fossa, LB Travis - Journal of the National …, 2019 - jnccn.org
Testicular cancer (TC) is the most common cancer among men aged 18 to 39 years. It is
highly curable, with a 10-year relative survival approaching 95% due to effective cisplatin …

Knowledge gaps and research priorities in immune checkpoint inhibitor–related pneumonitis. An official American thoracic society research statement

CR Sears, T Peikert, JD Possick, J Naidoo… - American journal of …, 2019 - atsjournals.org
Rationale: Immune checkpoint inhibitors (ICIs) have revolutionized cancer care but are
associated with unique adverse events, including potentially life-threatening pneumonitis …

Development of a best-practice clinical guideline for the use of bleomycin in the treatment of germ cell tumours in the UK

RA Watson, H De La Peña, MT Tsakok… - British Journal of …, 2018 - nature.com
Bleomycin, a cytotoxic chemotherapy agent, forms a key component of curative regimens for
lymphoma and germ cell tumours. It can be associated with severe toxicity, long-term …

Checkpoint inhibitor pneumonitis: mechanisms, characteristics, management strategies, and beyond

JE Reuss, K Suresh, J Naidoo - Current oncology reports, 2020 - Springer
Abstract Purpose of Review Checkpoint inhibitor pneumonitis (CIP) is a toxicity of immune
checkpoint blockade (ICB) that can be highly morbid and at times fatal. Here, we review the …

Primary mediastinal germ cell tumors: A thorough literature review

G Ozgun, L Nappi - Biomedicines, 2023 - mdpi.com
Primary mediastinal germ cell tumors (PMGCTs) are a rare type of cancer affecting young
adults. They have different molecular and clinical features compared to testicular germ cell …

Pulmonary toxicities from conventional chemotherapy

P Leger, AH Limper… - Clinics in chest …, 2017 - chestmed.theclinics.com
The development of lung infiltrates, shortness of breath, and gas exchange abnormalities in
a patient with malignancy treated with conventional cytotoxic chemotherapy often creates a …

The effect of concomitant use of Colony-Stimulating factors on bleomycin pulmonary toxicity–A systematic review and meta-analysis

SMS Sani, M Sahranavard, MJ Yazdanabad… - International …, 2022 - Elsevier
Background Changes in the incidence of bleomycin pulmonary toxicity (BPT) as a result of
adding colony-stimulating factors (CSF) to bleomycin regimens has been investigated in …

[HTML][HTML] A randomized phase III study of 72 h infusional versus bolus bleomycin in BEP (bleomycin, etoposide and cisplatin) chemotherapy to treat IGCCCG good …

J Shamash, SJ Sarker, R Huddart, S Harland, JK Joffe… - Annals of …, 2017 - Elsevier
Background Bleomycin is an integral part of combination chemotherapy in germ cell
tumours. Pulmonary toxicity often necessitates drug cessation and death occurs in 1%–2 …

[HTML][HTML] Bleomycin-induced lung toxicity in Hodgkin's lymphoma: risk factors in the positron emission tomography era

S Jennane, M Ababou, M El Haddad, OA Sahel… - Cureus, 2022 - ncbi.nlm.nih.gov
Methods This is a retrospective study conducted in the clinical Hematology Department of
Mohammed V Military Instruction Hospital, Rabat, Morocco. All patients with Hodgkin's …