Humoral immune responses are thought to play a major role in dengue virus-induced
immunopathology; however, little is known about the plasmablasts producing these …

Dengue has been recognized as one of the most important vector‐borne emerging
infectious diseases globally. Though dengue normally causes a self‐limiting infection, some …

Lack of a dengue hemorrhagic animal model recapitulating human dengue virus infection
has been a significant impediment in advancing our understanding of the early events …

Dengue virus (DENV) is one of the most significant human viral pathogens transmitted by
mosquitoes and can cause from an asymptomatic disease to mild undifferentiated fever …

Background Dengue is the most common mosquito-borne viral disease in humans.
Recently, there has been an epidemic shift of dengue from mainly affecting children to …

Acute undifferentiated febrile illness (AUFI) has been a diagnostic dilemma in the tropics.
Without accurate point-of-care tests, information on local pathogens and clinical parameters …

Introduction The early identification of patients at risk of severe dengue infection (DI) is
critical to guide clinical management. There is currently no validated laboratory test which …

Dengue is an acute viral disease caused by dengue virus (DENV), which is transmitted by
Aedes mosquitoes. Symptoms of DENV infection range from inapparent to severe and can …

There are no approved therapeutics for the treatment of dengue disease despite the global
prevalence of dengue virus (DENV) and its mosquito vectors. DENV infections can lead to …

Dengue é uma doença negligenciada de alta morbidade e mortalidade em crianças e
adultos, ocorrendo principalmente em regiões tropicais e subtropicais. O objetivo desse …