Candida sp. Infections in Patients with Diabetes Mellitus

CF Rodrigues, ME Rodrigues, M Henriques - Journal of clinical medicine, 2019 - mdpi.com
Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

[HTML][HTML] Susceptibility test for fungi: clinical and laboratorial correlations in medical mycology

A Alastruey-Izquierdo, MSC Melhem… - Revista do Instituto de …, 2015 - SciELO Brasil
During recent decades, antifungal susceptibility testing has become standardized and
nowadays has the same role of the antibacterial susceptibility testing in microbiology …

Rapid and accurate molecular identification of the emerging multidrug-resistant pathogen Candida auris

M Kordalewska, Y Zhao, SR Lockhart… - Journal of clinical …, 2017 - Am Soc Microbiol
Candida auris is an emerging multidrug-resistant fungal pathogen causing nosocomial and
invasive infections associated with high mortality. C. auris is commonly misidentified as …

A multicenter multinational study of abdominal candidiasis: epidemiology, outcomes and predictors of mortality

M Bassetti, E Righi, F Ansaldi, M Merelli… - Intensive care …, 2015 - Springer
Purpose Clinical data on patients with intra-abdominal candidiasis (IAC) is still scarce.
Methods We collected data from 13 hospitals in Italy, Spain, Brazil, and Greece over a 3 …

Nosocomial candidiasis: antifungal stewardship and the importance of rapid diagnosis

MA Pfaller, M Castanheira - Medical mycology, 2016 - academic.oup.com
Candidemia and other forms of candidiasis are associated with considerable excess
mortality and costs. Despite the addition of several new antifungal agents with improved …

Invasive mycoses: diagnostic challenges

L Ostrosky-Zeichner - The American journal of medicine, 2012 - Elsevier
Despite the availability of newer antifungal drugs, outcomes for patients with invasive fungal
infections (IFIs) continue to be poor, in large part due to delayed diagnosis and initiation of …

Biomarkers of infection and sepsis

SM Opal, X Wittebole - Critical care clinics, 2020 - criticalcare.theclinics.com
Intensive care unit (ICU) practitioners and emergency department clinicians are in urgent
need of a major upgrade in their access to accurate and fast microbial diagnosis (Table 1) …

An alternate pathophysiologic paradigm of sepsis and septic shock: implications for optimizing antimicrobial therapy

A Kumar - Virulence, 2014 - Taylor & Francis
The advent of modern antimicrobial therapy following the discovery of penicillin during the
1940s yielded remarkable improvements in case fatality rate of serious infections including …

Timing of susceptibility-based antifungal drug administration in patients with Candida bloodstream infection: correlation with outcomes

SA Grim, K Berger, C Teng, S Gupta… - Journal of …, 2012 - academic.oup.com
Objectives We sought to determine the impact of timing of appropriate antifungal therapy, as
assessed by susceptibility results, on patient survival. Methods Patients≥ 16 years of age …

Characteristics and risk factors for 28-day mortality of hospital acquired fungemias in ICUs: data from the EUROBACT study

JA Paiva, JM Pereira, A Tabah, A Mikstacki… - Critical Care, 2016 - Springer
Background To characterize and identify prognostic factors for 28-day mortality among
patients with hospital-acquired fungemia (HAF) in the Intensive Care Unit (ICU). Methods A …