Sexually transmitted infections (STIs) have been part of human life since ancient times, and
their symptoms affect quality of life, and sequelae are common. Socioeconomic and …

Most sexually transmitted infections (STIs) can be accurately diagnosed and treated during
asymptomatic carriage. Widespread screening for these STIs is therefore assumed to be an …

The performance of commonly used assays for diagnosis of syphilis varies considerably
depending on stage of infection and sample type. In response to the need for improved …

In spite of its immutable susceptibility to penicillin, Treponema pallidum (T. pallidum) subsp.
pallidum continues to cause millions of cases of syphilis each year worldwide, resulting in …

In this scoping review, we offer a comprehensive understanding of the current and recent
epidemiology, challenges, and emerging issues related to bacterial sexually transmitted …

Congenital syphilis is a major global cause of fetal loss, stillbirth, neonatal death, and
congenital infection. In 2020, the global rate of congenital syphilis was 425 cases per 100 …

The quest for a syphilis vaccine to provide protection from infection or disease began not
long after the isolation of the first Treponema pallidum subspecies pallidum (T. pallidum) …

The recent development of a system for long-term in vitro culture of the syphilis spirochete,
Treponema pallidum subsp. pallidum, has introduced the possibility of detailed genetic …

Background Central nervous system damage is an essential clinical feature that occurs in
the early or late stages of syphilis infection. The abnormal enhancement of microglial …

Background The incidence of syphilis has increased markedly in the past decade in high-
income countries, including Australia. To date, however, genomic studies of Treponema …