[HTML][HTML] Diversity and versatility of p38 kinase signalling in health and disease
B Canovas, AR Nebreda - Nature reviews Molecular cell biology, 2021 - nature.com
The ability of cells to deal with different types of stressful situations in a precise and
coordinated manner is key for survival and involves various signalling networks. Over the …
coordinated manner is key for survival and involves various signalling networks. Over the …
Neuroinflammation in Alzheimer's disease: current progress in molecular signaling and therapeutics
Alzheimer's disease, a neurodegenerative disease with amyloid beta accumulation as a
major hallmark, has become a dire global health concern as there is a lack of clear …
major hallmark, has become a dire global health concern as there is a lack of clear …
[HTML][HTML] Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review
B Sun, L Wu, Y Wu, C Zhang, L Qin… - Frontiers in …, 2020 - frontiersin.org
Centella asiatica (also known as Centella asiatica (L.) Urb. or Gotu kola) is a traditional
Chinese medicine with extensive medicinal value, which is commonly used in Southeast …
Chinese medicine with extensive medicinal value, which is commonly used in Southeast …
[HTML][HTML] Novel therapeutic approaches for Alzheimer's disease: an updated review
Alzheimer's disease (AD) is a progressive neurodegenerative disease and accounts for
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
[HTML][HTML] Targeting multiple signaling pathways in cancer: The rutin therapeutic approach
Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …
conventional therapies used in cancer prevention/treatment suffer from low efficacy …
[HTML][HTML] Involvement of p38 MAPK in synaptic function and dysfunction
C Falcicchia, F Tozzi, O Arancio, DM Watterson… - International journal of …, 2020 - mdpi.com
Many studies have revealed a central role of p38 MAPK in neuronal plasticity and the
regulation of long-term changes in synaptic efficacy, such as long-term potentiation (LTP) …
regulation of long-term changes in synaptic efficacy, such as long-term potentiation (LTP) …
Degradable polyprodrugs: design and therapeutic efficiency
Prodrugs are developed to increase the therapeutic properties of drugs and reduce their
side effects. Polyprodrugs emerged as highly efficient prodrugs produced by the …
side effects. Polyprodrugs emerged as highly efficient prodrugs produced by the …
Role of nuclear factor kappa B (NF-κB) signalling in neurodegenerative diseases: an mechanistic approach
S Singh, TG Singh - Current Neuropharmacology, 2020 - ingentaconnect.com
A transcriptional regulatory nuclear factor kappa B (NF-ΚB) protein is a modulator of cellular
biological activity via binding to a promoter region in the nucleus and transcribing various …
biological activity via binding to a promoter region in the nucleus and transcribing various …
[HTML][HTML] Functions of p38 MAP kinases in the central nervous system
Mitogen-activated protein (MAP) kinases are a central component in signaling networks in a
multitude of mammalian cell types. This review covers recent advances on specific functions …
multitude of mammalian cell types. This review covers recent advances on specific functions …
[HTML][HTML] Neuroprotective effects of ononin against the aluminium chloride-induced Alzheimer's disease in rats
Alzheimer's disease (AD) is a chronic neurodegenerative disease categorized by the
deficiency in the cognition and memory. Approximately 50 million peoples has the AD, which …
deficiency in the cognition and memory. Approximately 50 million peoples has the AD, which …