[HTML][HTML] The knowns and unknowns of neural adaptations to resistance training

J Škarabot, CG Brownstein, A Casolo… - European Journal of …, 2021 - Springer
The initial increases in force production with resistance training are thought to be primarily
underpinned by neural adaptations. This notion is firmly supported by evidence displaying …

Approaches to revealing the neural basis of muscle synergies: a review and a critique

VCK Cheung, K Seki - Journal of neurophysiology, 2021 - journals.physiology.org
The central nervous system (CNS) may produce coordinated motor outputs via the
combination of motor modules representable as muscle synergies. Identification of muscle …

[PDF][PDF] Motor unit

CJ Heckman, RM Enoka - Comprehensive physiology, 2012 - drive.google.com
Movement is accomplished by the controlled activation of motor unit populations. Our
understanding of motor unit physiology has been derived from experimental work on the …

Nonlinear input-output functions of motoneurons

MD Binder, RK Powers, CJ Heckman - Physiology, 2020 - journals.physiology.org
All movements are generated by the activation of motoneurons, and hence their input-output
properties define the final step in processing of all motor commands. A major challenge to …

Ageing reduces persistent inward current contribution to motor neurone firing: Potential mechanisms and the role of exercise

LBR Orssatto, AJ Blazevich… - The Journal of …, 2023 - Wiley Online Library
Nervous system deterioration is a primary driver of age‐related motor impairment. The motor
neurones, which act as the interface between the central nervous system and the muscles …

Estimates of persistent inward currents are reduced in upper limb motor units of older adults

AS Hassan, ME Fajardo, M Cummings… - The Journal of …, 2021 - Wiley Online Library
Ageing is a natural process causing alterations in the neuromuscular system, which
contributes to reduced quality of life. Motor unit (MU) contributes to weakness, but the …

Motoneuron excitability: the importance of neuromodulatory inputs

CJ Heckman, C Mottram, K Quinlan, R Theiss… - Clinical …, 2009 - Elsevier
The excitability of spinal motoneurons is both fundamental for motor behavior and essential
in diagnosis of neural disorders. There are two mechanisms for altering this excitability. The …

The potential for understanding the synaptic organization of human motor commands via the firing patterns of motoneurons

MD Johnson, CK Thompson… - Journal of …, 2017 - journals.physiology.org
Motoneurons are unique in being the only neurons in the CNS whose firing patterns can be
easily recorded in human subjects. This is because of the one-to-one relationship between …

The cellular basis for the generation of firing patterns in human motor units

OU Khurram, GEP Pearcey, MK Chardon, EH Kim… - Vertebrate …, 2022 - Springer
Motor units, which comprise a motoneuron and the set of muscle fibers it innervates, are the
fundamental neuromuscular transducers for all motor commands. The one to one …

[HTML][HTML] Gain control mechanisms in spinal motoneurons

MD Johnson, CJ Heckman - Frontiers in neural circuits, 2014 - frontiersin.org
Motoneurons provide the only conduit for motor commands to reach muscles. For many
years, motoneurons were in fact considered to be little more than passive “wires”. Systematic …