Mucosal immune responses to infection and vaccination in the respiratory tract

RC Mettelman, EK Allen, PG Thomas - Immunity, 2022 - cell.com
The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

Pathogenesis of COVID-19-induced ARDS: implications for an ageing population

MAT Acosta, BD Singer - European Respiratory Journal, 2020 - Eur Respiratory Soc
The coronavirus disease 2019 (COVID-19) pandemic has elicited a swift response by the
scientific community to elucidate the pathogenesis of severe acute respiratory syndrome …

Update on the features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report

HS Kulkarni, JS Lee, JA Bastarache… - American journal of …, 2022 - atsjournals.org
Advancements in methods, technology, and our understanding of the pathobiology of lung
injury have created the need to update the definition of experimental acute lung injury (ALI) …

[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression

G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …

Pathogenesis of acute respiratory distress syndrome

LA Huppert, MA Matthay… - Seminars in respiratory and …, 2019 - thieme-connect.com
Acute respiratory distress syndrome (ARDS) is a syndrome of acute respiratory failure
caused by noncardiogenic pulmonary edema. Despite five decades of basic and clinical …

Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19

R Alon, M Sportiello, S Kozlovski, A Kumar… - Nature Reviews …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …

A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair

K Sun, Y Li, J Jin - Signal transduction and targeted therapy, 2021 - nature.com
The response of immune cells in cardiac injury is divided into three continuous phases:
inflammation, proliferation and maturation. The kinetics of the inflammatory and proliferation …

Myc cooperates with Ras by programming inflammation and immune suppression

RM Kortlever, NM Sodir, CH Wilson, DL Burkhart… - Cell, 2017 - cell.com
The two oncogenes KRas and Myc cooperate to drive tumorigenesis, but the mechanism
underlying this remains unclear. In a mouse lung model of KRas G12D-driven adenomas …

[HTML][HTML] Differential roles of regulatory T cells in acute respiratory infections

M Jovisic, N Mambetsariev, BD Singer… - The Journal of …, 2023 - Am Soc Clin Investig
JCI - Differential roles of regulatory T cells in acute respiratory infections Go to JCI Insight About
Editors Consulting Editors For authors Publication ethics Alerts Advertising Job board Subscribe …

[HTML][HTML] Vitamin D alleviates lipopolysaccharide‑induced acute lung injury via regulation of the renin‑angiotensin system

J Xu, J Yang, J Chen, Q Luo… - Molecular …, 2017 - spandidos-publications.com
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are the clinical
manifestations of severe lung damage and respiratory failure. ALI and ARDS result are …