Transcriptional regulatory network of high-value active ingredients in medicinal plants

H Zheng, X Fu, J Shao, Y Tang, M Yu, L Li… - Trends in Plant …, 2023 - cell.com
High-value active ingredients in medicinal plants have attracted research attention because
of their benefits for human health, such as the antimalarial artemisinin, anticardiovascular …

Gut microbiota: therapeutic targets of ginseng against multiple disorders and ginsenoside transformation

Z Chen, Z Zhang, J Liu, H Qi, J Li, J Chen… - Frontiers in Cellular …, 2022 - frontiersin.org
Panax ginseng, as the king of Chinese herb, has significant therapeutic effects on obesity,
type 2 diabetes mellitus, fatty liver disease, colitis, diarrhea, and many other diseases. This …

Herb–drug interactions between Panax notoginseng or its biologically active compounds and therapeutic drugs: A comprehensive pharmacodynamic and …

Y Xie, C Wang - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Herbs, along with the use of herb–drug interactions (HDIs)
to combat diseases, are increasing in popularity worldwide. HDIs have two effects: favorable …

The mechanism of microglia-mediated immune inflammation in ischemic stroke and the role of natural botanical components in regulating microglia: A review

J Zeng, T Bao, K Yang, X Zhu, S Wang… - Frontiers in …, 2023 - frontiersin.org
Ischemic stroke (IS) is one of the most fatal diseases. Neuroimmunity, inflammation, and
oxidative stress play important roles in various complex mechanisms of IS. In particular, the …

Ginsenosides emerging as both bifunctional drugs and nanocarriers for enhanced antitumor therapies

H Wang, Y Zheng, Q Sun, Z Zhang, M Zhao… - Journal of …, 2021 - Springer
Ginsenosides, the main components isolated from Panax ginseng, can play a therapeutic
role by inducing tumor cell apoptosis and reducing proliferation, invasion, metastasis; by …

Notoginsenoside R1 protects against myocardial ischemia/reperfusion injury in mice via suppressing TAK1-JNK/p38 signaling

J Zeng, H Shi, F Ren, X Zhao, Q Chen… - Acta Pharmacologica …, 2023 - nature.com
Previous studies show that notoginsenoside R1 (NG-R1), a novel saponin isolated from
Panax notoginseng, protects kidney, intestine, lung, brain and heart from ischemia …

Advancing herbal medicine: enhancing product quality and safety through robust quality control practices

H Wang, Y Chen, L Wang, Q Liu, S Yang… - Frontiers in …, 2023 - frontiersin.org
This manuscript provides an in-depth review of the significance of quality control in herbal
medication products, focusing on its role in maintaining efficiency and safety. With a …

Ginsenoside Rk3 is a novel PI3K/AKT-targeting therapeutics agent that regulates autophagy and apoptosis in hepatocellular carcinoma

L Qu, Y Liu, J Deng, X Ma, D Fan - Journal of Pharmaceutical Analysis, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Ginsenoside Rk3, an important and rare saponin in heat-treated ginseng, is generated from …

[HTML][HTML] Ginsenoside Rk3 ameliorates Aβ-induced neurotoxicity in APP/PS1 model mice via AMPK signaling pathway

L She, L Xiong, L Li, J Zhang, J Sun, H Wu… - Biomedicine & …, 2023 - Elsevier
Alzheimer's disease (AD) has become a major public health problem affecting the elderly
population, and there is currently no effective treatment. Although the pathogenesis of AD is …

Ginsenoside and its therapeutic potential for cognitive impairment

H Feng, M Xue, H Deng, S Cheng, Y Hu, C Zhou - Biomolecules, 2022 - mdpi.com
Cognitive impairment (CI) is one of the major clinical features of many neurodegenerative
diseases. It can be aging-related or even appear in non-central nerve system (CNS) …