Genetic predisposition to gallbladder stones

H Wittenburg, F Lammert - Seminars in liver disease, 2007 - thieme-connect.com
Geographic and ethnic differences in gallstone prevalence rates and familial clustering of
cholelithiasis imply that genetic factors influence the risk of gallstone formation. Recently …

In vivo macrophage-specific RCT and antioxidant and antiinflammatory HDL activity measurements: New tools for predicting HDL atheroprotection

JC Escolà-Gil, N Rotllan, J Julve, F Blanco-Vaca - Atherosclerosis, 2009 - Elsevier
The beneficial therapeutic effects of raising HDL cholesterol are proving difficult to confirm in
humans. The evaluation of antiatherogenic functions of HDL is an important area of research …

Atheroprotective reverse cholesterol transport pathway is defective in familial hypercholesterolemia

N Bellanger, A Orsoni, Z Julia, N Fournier… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Low high-density lipoprotein (HDL) cholesterol levels are frequently observed in
familial hypercholesterolemia (FH) and might be associated with functional alterations of …

Plasma lipid transfer proteins and cardiovascular disease. The Framingham Heart Study

SJ Robins, A Lyass, RW Brocia, JM Massaro… - Atherosclerosis, 2013 - Elsevier
OBJECTIVE: Cholesteryl ester transfer protein (CETP) and phospholipid transfer protein
(PLTP) are two genetically-related plasma proteins involved in the exchange of cholesteryl …

Cholesteryl ester transfer protein: the controversial relation to atherosclerosis and emerging new biological roles

HCF Oliveira, EC de Faria - IUBMB life, 2011 - Wiley Online Library
Cholesteryl ester transfer protein (CETP) exerts a profound impact on high‐density
lipoprotein (HDL) metabolism and, consequently, on the risk of atherosclerosis development …

Cholesteryl ester transfer protein expression partially attenuates the adverse effects of SR-BI receptor deficiency on cholesterol metabolism and atherosclerosis

M El Bouhassani, S Gilibert, M Moreau… - Journal of Biological …, 2011 - ASBMB
Scavenger receptor SR-BI significantly contributes to HDL cholesterol metabolism and
atherogenesis in mice. However, the role of SR-BI may not be as pronounced in humans …

Torcetrapib differentially modulates the biological activities of HDL2 and HDL3 particles in the reverse cholesterol transport pathway

G Catalano, Z Julia, E Frisdal, B Vedie… - … , and vascular biology, 2009 - Am Heart Assoc
Objective—Therapeutic strategies to raise low plasma HDL-cholesterol levels, with
concomitant normalization of the intravascular metabolism, physicochemical properties, and …

Novel role of cholesteryl ester transfer protein (CETP): attenuation of adiposity by enhancing lipolysis and brown adipose tissue activity

HF Raposo, P Forsythe, B Chausse, JZ Castelli… - Metabolism, 2021 - Elsevier
Objective The systemic function of CETP has been well characterized. CETP plasma activity
reduces HDL cholesterol and thus increases the risk of atherosclerosis. Here, we …

Overexpression of apolipoprotein CIII increases and CETP reverses diet-induced obesity in transgenic mice

AG Salerno, TR Silva, MEC Amaral… - International Journal of …, 2007 - nature.com
Objective: We recently described that hypertriglyceridemic apolipoprotein (apo) CIII
transgenic mice show increased whole body metabolic rate. In this study, we used these apo …

Lipid transfer proteins: past, present and perspectives

ECR Quintão, PM Cazita - Atherosclerosis, 2010 - Elsevier
Lipid transfer proteins (PLTP and CETP) play roles in atherogenesis by modifying the
arterial intima cholesterol content via altering the concentration and function of plasma …