Botulinum toxin in the management of children with cerebral palsy

I Multani, J Manji, T Hastings-Ison, A Khot, K Graham - Pediatric Drugs, 2019 - Springer
During the past 25 years, botulinum toxin type A (BoNT-A) has become the most widely used
medical intervention in children with cerebral palsy. In this review we consider the gaps in …

Spasticity after stroke: physiology, assessment and treatment

A Thibaut, C Chatelle, E Ziegler, MA Bruno… - Brain injury, 2013 - Taylor & Francis
Background: Spasticity following a stroke occurs in about 30% of patients. The mechanisms
underlying this disorder, however, are not well understood. Method: This review aims to …

Prevalence and risk factors for spasticity after stroke: a systematic review and meta-analysis

H Zeng, J Chen, Y Guo, S Tan - Frontiers in neurology, 2021 - frontiersin.org
Background: Spasticity is a common sequela of stroke. The incidence of poststroke spasticity
(PSS) has not been systematically reviewed in recent years, and some risk factors remain …

A new definition of poststroke spasticity and the interference of spasticity with motor recovery from acute to chronic stages

S Li, GE Francisco, WZ Rymer - … and Neural Repair, 2021 - journals.sagepub.com
The relationship of poststroke spasticity and motor recovery can be confusing.“True” motor
recovery refers to return of motor behaviors to prestroke state with the same end-effectors …

Phenomenology in nursing studies: New perspectives

D Zahavi, KMM Martiny - International journal of nursing studies, 2019 - Elsevier
Nursing studies have for decades drawn on the philosophical tradition of phenomenology
when developing their own methodology and theoretical foundation. This use and …

New insights into the pathophysiology of post-stroke spasticity

S Li, GE Francisco - Frontiers in human neuroscience, 2015 - frontiersin.org
Spasticity is one of many consequences after stroke. It is characterized by a velocity-
dependent increase in resistance during passive stretch, resulting from hyperexcitability of …

Muscle architecture, growth, and biological Remodelling in cerebral palsy: a narrative review

GG Handsfield, S Williams, S Khuu, G Lichtwark… - BMC Musculoskeletal …, 2022 - Springer
Cerebral palsy (CP) is caused by a static lesion to the brain occurring in utero or up to the
first 2 years of life; it often manifests as musculoskeletal impairments and movement …

Stop using the Ashworth Scale for the assessment of spasticity

JFM Fleuren, GE Voerman… - Journal of Neurology …, 2010 - jnnp.bmj.com
Aim: Many studies have been performed on the methodological qualities of the (modified)
Ashworth Scale but overall these studies seem inconclusive. The aim of this study was to …

Poststroke spasticity: sequelae and burden on stroke survivors and caregivers

RD Zorowitz, PJ Gillard, M Brainin - Neurology, 2013 - AAN Enterprises
Among the estimated 20% to 40% of stroke survivors who develop spasticity, the burden of
this condition on patients, caregivers, and society is substantial. Stroke survivors with …

Pathophysiology, classification and comorbidities after traumatic spinal cord injury

J Guest, N Datta, G Jimsheleishvili… - Journal of personalized …, 2022 - mdpi.com
The spinal cord is a conduit within the central nervous system (CNS) that provides ongoing
communication between the brain and the rest of the body, conveying complex sensory and …