Autoimmune diseases are associated with a dramatically increased risk of atherosclerotic
cardiovascular disease and its clinical manifestations. The increased risk is consistent with …

Type II collagen (CII) is expressed exclusively in the joint articular. Although the relationship
between anti-CII immunity and human rheumatoid arthritis (RA) has been studied for a long …

The immune mechanisms that mediate synovitis and joint destruction in rheumatoid arthritis
(RA) remain poorly defined. Although increased levels of CD8+ T cells have been described …

Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) have key differences in clinical
presentation, radiographic findings, comorbidities and pathogenesis to distinguish between …

Background: Several anticitrullinated protein/peptide antibodies (ACPA) assays have been
reported to be of diagnostic value for rheumatoid arthritis (RA). We evaluated the technical …

Rheumatoid arthritis (RA) is a classic example of an autoimmune disorder, with chronic
inflammation of the synovial membrane, and deterioration of cartilage and bone in the …

Previous studies in type 1 diabetes (T1D) in the nonobese diabetic mouse demonstrated
that a crucial insulin epitope (B: 9-23) is presented to diabetogenic CD4 T cells by IAg7 in a …

Objective: To investigate whether rheumatoid factor isotypes and anti-cyclic citrullinated
peptide (anti-CCP) antibodies are related to clinical response in patients with rheumatoid …

Our aim is to assess the prevalence and associated clinical features of anti-CCP (cyclic
citrullinated peptide) antibodies for RF (rheumatoid factor)-positive and RF-negative …

Rheumatic diseases, such as rheumatoid and psoriatic arthritis are systemic inflammatory
conditions characterized by a chronic form of arthritis, often leading to irreversible joint …