Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

The programmed cell death (PCD) of developing cells is considered an essential adaptive
process that evolved to serve diverse roles. We review the putative adaptive functions of …

During retinal development, neuroepithelial progenitor cells divide in either a symmetric
proliferative mode, in which both daughter cells remain mitotic, or in a neurogenic mode, in …

Cone photoreceptors in fish are typically arranged into a precise, reiterated pattern known
as a “cone mosaic.” Cone mosaic patterns can vary in different fish species and in response …

Teleost fish are distinguished by their ability to constitutively generate new neurons in the
adult central nervous system ('adult neurogenesis'), and to regenerate whole neurons after …

The retinas of teleost fish have long been of interest to developmental neurobiologists for
their persistent plasticity during growth, life history changes, and response to injury. Because …

The retinas of adult teleost fish can regenerate neurons following injury. The current study
provides the first documentation of functional whole retina regeneration in the zebrafish …

Apoptosis plays important roles in embryogenesis, tissue homeostasis, and immune system
regulation. The zebrafish (Danio rerio) is a powerful vertebrate model organism that has …

Programmed cell death occurs naturally, as a physiological process, during the embryonic
development of multicellular organisms. In the retina, which belongs to the central nervous …

Background Microglia colonize the developing vertebrate central nervous system coincident
with the detection of developmental apoptosis. Our understanding of apoptosis in intact …