The PC12 cell line is one of the most commonly used in neuroscience research, including
studies on neurotoxicity, neuroprotection, neurosecretion, neuroinflammation, and …

Selective elimination of synaptic connections is a common phenomenon which occurs
during both developmental and pathological conditions. Glial cells have a central role in the …

The PC12 cell line is a classical neuronal cell model due to its ability to acquire the
sympathetic neurons features when deal with nerve growth factor (NGF). In the present …

Carbon nanotubes (CNTs), as kinds of conductive carbon nanomaterials, were widely
applied in neural tissue engineering due to their excellent electrical conductivity and good …

The increasing use of carbon nanotubes (CNTs) in biomedical applications has garnered a
great concern on their potential negative effects to human health. CNTs have been reported …

Medicinal cannabis has shown promise for the symptomatic treatment of Parkinson's
disease (PD), but patient exposure to whole plant mixtures may be undesirable due to …

Major histocompatibility complex class I (MHC-I) has been implicated in several types of
neuroplasticity phenomena. Interferon beta-1b (IFN-β) increases MHC-I expression by …

Neurodegenerative diseases are generally characterized clinically by the selective loss of a
distinct subset of neurons and a slow progressive course. Mounting evidence in vivo …

Abnormal biometal homeostasis is a central feature of many neurodegenerative disorders
including Alzheimer's disease (AD), Parkinson's disease (PD), and motor neuron disease …

The frequent comorbidity of Autism Spectrum Disorders (ASDs) with epilepsy suggests a
shared underlying genetic susceptibility; several genes, when mutated, can contribute to …