Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Exercise benefits in cardiovascular diseases: from mechanisms to clinical implementation

PL Valenzuela, LM Ruilope… - European Heart …, 2023 - academic.oup.com
There is a pandemic of physical inactivity that appears to parallel the widespread
prevalence of cardiovascular disease (CVD). Yet, regular physical activity (PA) and exercise …

The regulation of fat metabolism during aerobic exercise

A Muscella, E Stefàno, P Lunetti, L Capobianco… - Biomolecules, 2020 - mdpi.com
Since the lipid profile is altered by physical activity, the study of lipid metabolism is a
remarkable element in understanding if and how physical activity affects the health of both …

Tuning fatty acid oxidation in skeletal muscle with dietary fat and exercise

AM Fritzen, AM Lundsgaard, B Kiens - Nature Reviews Endocrinology, 2020 - nature.com
Both the consumption of a diet rich in fatty acids and exercise training result in similar
adaptations in several skeletal muscle proteins. These adaptations are involved in fatty acid …

Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease

JFC Glatz, JJFP Luiken, A Bonen - Physiological reviews, 2010 - journals.physiology.org
Long-chain fatty acids and lipids serve a wide variety of functions in mammalian
homeostasis, particularly in the formation and dynamic properties of biological membranes …

Short‐term sprint interval versus traditional endurance training: similar initial adaptations in human skeletal muscle and exercise performance

MJ Gibala, JP Little, M Van Essen… - The Journal of …, 2006 - Wiley Online Library
Brief, intense exercise training may induce metabolic and performance adaptations
comparable to traditional endurance training. However, no study has directly compared …

The molecular bases of training adaptation

VG Coffey, JA Hawley - Sports medicine, 2007 - Springer
Skeletal muscle is a malleable tissue capable of altering the type and amount of protein in
response to disruptions to cellular homeostasis. The process of exerciseinduced adaptation …

Exercise induces transient transcriptional activation of the PGC‐1α gene in human skeletal muscle

H Pilegaard, B Saltin, PD Neufer - 2003 - Wiley Online Library
Endurance exercise training induces mitochondrial biogenesis in skeletal muscle. The
peroxisome proliferator activated receptor co‐activator 1α (PGC‐1α) has recently been …

[PDF][PDF] Physical activity/exercise and type 2 diabetes

RJ Sigal, GP Kenny, DH Wasserman… - Diabetes …, 2004 - paulogentil.com
For decades, exercise has been consid-ered a cornerstone of diabetes management, along
with diet and medication. However, high-quality evidence on the importance of exercise and …

Eating, exercise, and “thrifty” genotypes: connecting the dots toward an evolutionary understanding of modern chronic diseases

MV Chakravarthy, FW Booth - Journal of applied physiology, 2004 - journals.physiology.org
Survival of Homo sapiens during evolution was dependent on the procurement of food,
which in turn was dependent on physical activity. However, food supply was never …