The employment of machine learning approaches has shown promising results in predicting
cancer. In the current study, polymorphisms data of five single nucleotide polymorphisms …

Advances in the management of patients with head and neck squamous cell carcinoma
(HNSCC) have not significantly changed the prognosis of this tumor over the past five …

Defects in the DNA damage repair pathway contribute to cancer. The major pathway for
oxidative DNA damage repair is base excision repair (BER). Although BER pathway genes …

In first part of this study, a systematic review was designed to explore the involvement of
CYP1A1 and GSTP1 genes in breast cancerogenesis. Based on systematic review, we …

XRCC1 is a scaffold protein that provides for interaction of DNA polymerase, DNA ligase
and damaged DNA. Genotyping was done for the five non-synonymous and synonymous …

Introduction: Head and neck squamous cell carcinomas (HNSSCs) are one of the leading
causes of cancer-associated death worldwide. Although certain behavioral risk factors are …

Background Balance of DNA damage and proper repair plays an important role in
progression of bladder cancer. Here we aimed to assess the associations of nineteen …

Rheumatoid arthritis (RA) is one of the most common autoimmune diseases globally, and is
an important public health concern, associating with early death and systemic complications …

This study conducted an in-depth analysis combining computational and experimental
verifications of the deleterious missense mutations associated with the SLC29A4 protein …

BACKGROUND: Reduced efficiency of DNA repair systems has long been a suspected
factor in increasing the risk of cancer. OBJECTIVE: In this work we investigate influence of …