The world population is ageing rapidly. As society ages, the incidence of physical limitations
is dramatically increasing, which reduces the quality of life and increases healthcare …

The concept of 'successful aging'has long intrigued the scientific community. Despite this
long-standing interest, a consensus definition has proven to be a difficult task, due to the …

In 2008, we published an article arguing that the age-related loss of muscle strength is only
partially explained by the reduction in muscle mass and that other physiologic factors …

Dynapenia (pronounced dahy-nuh-pē-nē-a, Greek translation for poverty of strength, power,
or force) is the age-associated loss of muscle strength that is not caused by neurologic or …

Beta oscillations are involved in movement and have previously been linked to levels of the
inhibitory neurotransmitter GABA. We examined changes in beta oscillations during rest and …

Forty years ago, CD Marsden proposed that blepharospasm should be considered a form of
adult‐onset focal dystonia. In the present paper, we provide a comprehensive overview of …

Classical studies in animal preparations suggest a strong role for spinal control of posture. In
humans it is now established that the cerebral cortex contributes to postural control of …

Transcranial magnetic stimulation (TMS)-induced silent periods provide an in vivo measure
of human motor cortical inhibitory function. Cortical silent periods (cSP, also sometimes …

Aging is associated with dramatic reductions in muscle strength and motor control, and
many of these agerelated changes in muscle function result from adaptations in the central …

The ability to inhibit actions, one of the hallmarks of human motor control, appears to decline
with advancing age. Evidence for a link between changes in inhibitory functions and poor …