The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

Atherosclerosis, characterized by lipid‐rich plaques in the arterial wall, is an age‐related
disorder and a leading cause of mortality worldwide. However, the specific mechanisms …

Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …

Moyamoya disease (MMD) shows progressive cerebral angiopathy characterized by
bilateral internal carotid artery stenosis and abnormal collateral vessels. Although∼ 15% of …

Bone vasculature plays a vital role in bone development, remodeling and homeostasis. New
blood vessel formation is crucial during both primary bone development as well as fracture …

Endothelial progenitor cells are known to reverse acute kidney injury by paracrine
mechanisms. We previously found that microvesicles released from these progenitor cells …

Tissue engineered vascular grafts (TEVGs) are beginning to achieve clinical success and
hold promise as a source of grafting material when donor grafts are unsuitable or …

The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth
muscle, by releasing vasodilator substances. The best characterized endothelium‐derived …

The vascular system delivers oxygen and nutrients to every cell in the vertebrate organism.
Hypoxia-inducible factor 1 (HIF-1) is a master regulator of hypoxic/ischaemic vascular …

Adiponectin is the most abundant peptide secreted by adipocytes, being a key component in
the interrelationship between adiposity, insulin resistance and inflammation. Central obesity …