A new generation of AD biomarkers: 2019 to 2021

J Hawksworth, E Fernandez, K Gevaert - Ageing research reviews, 2022 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia and cases are rising
worldwide. The effort to fight this disease is hampered by a lack of disease-modifying …

Nutrition in Alzheimer's disease: A review of an underappreciated pathophysiological mechanism

J Jiang, H Shi, S Jiang, A Wang, X Zou, Y Wang… - Science China Life …, 2023 - Springer
Alzheimer's disease (AD) is the leading cause of dementia in older individuals and is an
escalating challenge to global public health. Pharmacy therapy of AD is one of the well …

Instant dark tea alleviates hyperlipidaemia in high-fat diet-fed rat: from molecular evidence to redox balance and beyond

S Qin, Z He, Y Wu, C Zeng, Z Zheng, H Zhang… - Frontiers in …, 2022 - frontiersin.org
Instant dark tea (IDT) is a new product gaining increasing attention because it is convenient
and can endow significant health benefit to consumers, which is partially attributed to its high …

Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus

S Weiner, A Junkkari, M Sauer, A Luikku… - Fluids and Barriers of …, 2023 - Springer
Abstract Background Idiopathic Normal pressure hydrocephalus (iNPH) is a form of adult
hydrocephalus that is clinically characterized by progressive gait impairment, cognitive …

Exploring the role of lipid-binding proteins and oxidative stress in neurodegenerative disorders: A focus on the Neuroprotective effects of Nutraceutical …

G Scarfò, R Piccarducci, S Daniele, F Franzoni… - Antioxidants, 2022 - mdpi.com
The human brain is primarily composed of lipids, and their homeostasis is crucial to carry on
normal neuronal functions. In order to provide an adequate amount of lipid transport in and …

Continuous positive airway pressure reduces plasma neurochemical levels in patients with OSA: a pilot study

WT Liu, HT Huang, HY Hung, SY Lin, WH Hsu, FY Lee… - Life, 2023 - mdpi.com
Obstructive sleep apnea (OSA) is a risk factor for neurodegenerative diseases. This study
determined whether continuous positive airway pressure (CPAP), which can alleviate OSA …

Astrocytic functions and lipid metabolism: Correlations and therapeutic targets in Alzheimer's disease and glioblastoma

X Zhang, R Gao, L Yang, Y Zhu, T Zhang… - Clinical and …, 2024 - Wiley Online Library
Background The brain is a central key organ of the body containing the second highest lipid
content only after adipose tissue. Lipids as the main structural components of biological …

Heart fatty acid-binding protein is associated with phosphorylated tau and longitudinal cognitive changes

Y Fu, ZT Wang, LY Huang, CC Tan, XP Cao… - Frontiers in Aging …, 2022 - frontiersin.org
Background Perturbation of lipid metabolism is associated with Alzheimer's disease (AD).
Heart fatty acid-binding protein (HFABP) is an adipokine playing an important role in lipid …

[HTML][HTML] Revealing the heterogeneity of plasma protein and cognitive decline trajectory among Mild Cognitive Impairment patients by clustering of brain atrophy …

M Nguyen, B Pham, T Vo, H Ha - Brain Multiphysics, 2024 - Elsevier
Alzheimer's disease (AD) is suggested to be a heterogeneous disorder, but limited studies
explore the heterogeneity of the Mild Cognitive Impairment (MCI) stage. This study aimed to …

A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer's disease patients from controls

I Pesämaa, SA Müller, S Robinson, A Darcher… - Molecular …, 2023 - Springer
Background With the emergence of microglia-modulating therapies there is an urgent need
for reliable biomarkers to evaluate microglial activation states. Methods Using mouse …