Disorders of bone remodeling
X Feng, JM McDonald - Annual Review of Pathology …, 2011 - annualreviews.org
The skeleton provides mechanical support for stature and locomotion, protects vital organs,
and controls mineral homeostasis. A healthy skeleton must be maintained by constant bone …
and controls mineral homeostasis. A healthy skeleton must be maintained by constant bone …
[HTML][HTML] A review of the latest insights into the mechanism of action of strontium in bone
D Marx, AR Yazdi, M Papini, M Towler - Bone reports, 2020 - Elsevier
Interest in strontium (Sr) has persisted over the last three decades due to its unique
mechanism of action: it simultaneously promotes osteoblast function and inhibits osteoclast …
mechanism of action: it simultaneously promotes osteoblast function and inhibits osteoclast …
Materials-based nanotherapeutics for injured and diseased bone
Severe injuries and diseases of bone tissue caused by congenital disorder, extrinsic trauma,
infection, and osteosarcoma resection face significant challenges for complete recovery. The …
infection, and osteosarcoma resection face significant challenges for complete recovery. The …
[图书][B] Animal models for the study of human disease
PM Conn - 2017 - books.google.com
Animal Models for the Study of Human Disease, Second Edition, provides needed
information on model sharing, animal alternatives, animal ethics and access to databanks of …
information on model sharing, animal alternatives, animal ethics and access to databanks of …
Hormesis and medicine
EJ Calabrese - British journal of clinical pharmacology, 2008 - Wiley Online Library
Evidence is presented which supports the conclusion that the hormetic dose–response
model is the most common and fundamental in the biological and biomedical sciences …
model is the most common and fundamental in the biological and biomedical sciences …
Hormesis: from marginalization to mainstream: a case for hormesis as the default dose-response model in risk assessment
EJ Calabrese - Toxicology and applied pharmacology, 2004 - Elsevier
The paper provides an account of how the hormetic dose response has emerged in recent
years as a serious dose-response model in toxicology and risk assessment after decades of …
years as a serious dose-response model in toxicology and risk assessment after decades of …
Essential role of nuclear factor of activated T cells (NFAT)-mediated Wnt signaling in osteoblast differentiation induced by strontium ranelate
O Fromigué, E Haÿ, A Barbara, PJ Marie - Journal of Biological Chemistry, 2010 - ASBMB
The antiosteoporotic treatment strontium ranelate (SrRan) was shown to increase bone
mass and strength by dissociating bone resorption and bone formation. To identify the …
mass and strength by dissociating bone resorption and bone formation. To identify the …
Transcriptional regulation of bone and joint remodeling by NFAT
D Sitara, AO Aliprantis - Immunological reviews, 2010 - Wiley Online Library
Osteoporosis and arthritis are highly prevalent diseases and a significant cause of morbidity
and mortality worldwide. These diseases result from aberrant tissue remodeling leading to …
and mortality worldwide. These diseases result from aberrant tissue remodeling leading to …
The role of Ca2+/Calcineurin/NFAT signalling pathway in osteoblastogenesis
R Ren, J Guo, Y Chen, Y Zhang, L Chen… - Cell …, 2021 - Wiley Online Library
The bone remodelling process is closely related to bone health. Osteoblasts and osteoclasts
participate in the bone remodelling process under the regulation of various factors inside …
participate in the bone remodelling process under the regulation of various factors inside …
TLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NF-κB
P Zhang, J Liu, Q Xu, G Harber, X Feng… - Journal of Biological …, 2011 - ASBMB
Osteolytic diseases, including rheumatoid arthritis, osteomyelitis, and periodontitis, are
usually associated with bacterial infections. However, the precise mechanisms by which …
usually associated with bacterial infections. However, the precise mechanisms by which …