International consensus statement on allergy and rhinology: rhinosinusitis 2021

RR Orlandi, TT Kingdom, TL Smith… - International forum of …, 2021 - Wiley Online Library
I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

Z Pang, R Raudonis, BR Glick, TJ Lin, Z Cheng - Biotechnology advances, 2019 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …

Bacteriophage therapy against Pseudomonas aeruginosa biofilms: a review

Z Chegini, A Khoshbayan, M Taati Moghadam… - Annals of clinical …, 2020 - Springer
Abstract Multi-Drug Resistant (MDR) Pseudomonas aeruginosa is one of the most important
bacterial pathogens that causes infection with a high mortality rate due to resistance to …

[HTML][HTML] Phage therapy in the resistance era: where do we stand and where are we going?

T Luong, AC Salabarria, DR Roach - Clinical therapeutics, 2020 - Elsevier
Purpose Widespread antibiotic-resistant bacteria are threatening the arsenal of existing
antibiotics. Not only are antibiotics less likely to be effective today, but their extensive use …

Bacteriophage therapy: clinical trials and regulatory hurdles

LL Furfaro, MS Payne, BJ Chang - Frontiers in cellular and infection …, 2018 - frontiersin.org
Increasing reports of antimicrobial resistance and limited new antibiotic discoveries and
development have fuelled innovation in other research fields and led to a revitalization of …

Impact of antibiotics on the human microbiome and consequences for host health

DV Patangia, C Anthony Ryan, E Dempsey… - …, 2022 - Wiley Online Library
It is well established that the gut microbiota plays an important role in host health and is
perturbed by several factors including antibiotics. Antibiotic‐induced changes in microbial …

Recent advances in anti-virulence therapeutic strategies with a focus on dismantling bacterial membrane microdomains, toxin neutralization, quorum-sensing …

O Fleitas Martínez, MH Cardoso, SM Ribeiro… - Frontiers in cellular …, 2019 - frontiersin.org
Antimicrobial resistance constitutes one of the major challenges facing humanity in the
Twenty-First century. The spread of resistant pathogens has been such that the possibility of …

Successful adjunctive use of bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa infection in a cystic fibrosis patient

N Law, C Logan, G Yung, CLL Furr, SM Lehman… - Infection, 2019 - Springer
Introduction We describe the use of bacteriophage therapy in a 26-year-old cystic fibrosis
(CF) patient awaiting lung transplantation. Hospital Course The patient developed multidrug …

Clinical indications and compassionate use of phage therapy: personal experience and literature review with a focus on osteoarticular infections

O Patey, S McCallin, H Mazure, M Liddle, A Smithyman… - Viruses, 2018 - mdpi.com
The history of phage therapy started with its first clinical application in 1919 and continues its
development to this day. Phages continue to lack any market approval in Western medicine …

Efflux Pump-Driven Antibiotic and Biocide Cross-Resistance in Pseudomonas aeruginosa Isolated from Different Ecological Niches: A Case Study in the …

A Amsalu, SA Sapula, M De Barros Lopes, BJ Hart… - Microorganisms, 2020 - mdpi.com
Pseudomonas aeruginosa is an opportunistic pathogen displaying high intrinsic
antimicrobial resistance and the ability to thrive in different ecological environments. In this …