Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants
Abstract In late 2022, SARS-CoV-2 Omicron subvariants have become highly diversified,
and XBB is spreading rapidly around the world. Our phylogenetic analyses suggested that …
and XBB is spreading rapidly around the world. Our phylogenetic analyses suggested that …
Evolution and neutralization escape of the SARS-CoV-2 BA. 2.86 subvariant
Abstract Omicron BA. 2.86 subvariant differs from Omicron BA. 2 as well as recently
circulating variants by over 30 mutations in the spike protein alone. Here we report on the …
circulating variants by over 30 mutations in the spike protein alone. Here we report on the …
Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA. 1 attenuation
Abstract The SARS-CoV-2 Omicron variant is more immune evasive and less virulent than
other major viral variants that have so far been recognized,,,,,,,,,,–. The Omicron spike (S) …
other major viral variants that have so far been recognized,,,,,,,,,,–. The Omicron spike (S) …
[HTML][HTML] The SARS-CoV-2 spike S375F mutation characterizes the Omicron BA. 1 variant
I Kimura, D Yamasoba, H Nasser, J Zahradnik… - Iscience, 2022 - cell.com
Recent studies have revealed the unique virological characteristics of Omicron, particularly
those of its spike protein, such as less cleavage efficacy in cells, reduced ACE2 binding …
those of its spike protein, such as less cleavage efficacy in cells, reduced ACE2 binding …
[HTML][HTML] Virological characteristics of the SARS-CoV-2 Omicron BA. 2.75 variant
Summary The SARS-CoV-2 Omicron BA. 2.75 variant emerged in May 2022. BA. 2.75 is a
BA. 2 descendant but is phylogenetically distinct from BA. 5, the currently predominant BA. 2 …
BA. 2 descendant but is phylogenetically distinct from BA. 5, the currently predominant BA. 2 …
Dual inhibition of vacuolar-ATPase and TMPRSS2 is required for complete blockade of SARS-CoV-2 entry into cells
S Icho, E Rujas, K Muthuraman, J Tam… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
An essential step in the infection life cycle of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is the proteolytic activation of the viral spike (S) protein, which …
coronavirus 2 (SARS-CoV-2) is the proteolytic activation of the viral spike (S) protein, which …
The spike-stabilizing D614G mutation interacts with S1/S2 cleavage site mutations to promote the infectious potential of SARS-CoV-2 variants
S Gellenoncourt, N Saunders, R Robinot… - Journal of …, 2022 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remained genetically
stable during the first 3 months of the pandemic, before acquiring a D614G spike mutation …
stable during the first 3 months of the pandemic, before acquiring a D614G spike mutation …
SARS-CoV-2 reinfections during the first three major COVID-19 waves in Bulgaria
GK Marinov, M Mladenov, A Rangachev, I Alexiev - PLoS One, 2022 - journals.plos.org
Background The COVID-19 pandemic has had a devastating impact on the world over the
past two years (2020-2021). One of the key questions about its future trajectory is the …
past two years (2020-2021). One of the key questions about its future trajectory is the …
Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern
E Vanhulle, T D'huys, B Provinciael… - Frontiers in Cellular …, 2022 - frontiersin.org
Urtica dioica agglutinin (UDA) is a carbohydrate-binding small monomeric protein isolated
from stinging nettle rhizomes. It inhibits replication of a broad range of viruses, including …
from stinging nettle rhizomes. It inhibits replication of a broad range of viruses, including …
Identification of a SARS-CoV-2 host metalloproteinase-dependent entry pathway differentially used by SARS-CoV-2 and variants of concern Alpha, Delta, and …
M Benlarbi, G Laroche, C Fink, K Fu, RP Mulloy… - bioRxiv, 2022 - biorxiv.org
To infect cells, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) binds to
angiotensin converting enzyme 2 (ACE2) via its spike glycoprotein (S), delivering its …
angiotensin converting enzyme 2 (ACE2) via its spike glycoprotein (S), delivering its …