Aquatic environments are often contaminated with complex mixtures of chemicals that may
pose a risk to ecosystems and human health. This contamination cannot be addressed with …

The brain is very sensitive to changes in redox status; thus maintaining redox homeostasis
in the brain is critical for the prevention of accumulating oxidative damage. Aging is the …

Abstract Effect-based methods including cell-based bioassays, reporter gene assays and
whole-organism assays have been applied for decades in water quality monitoring and …

Abstract Background: Bisphenol A (BPA) is a chemical with widespread human exposure
suspected of causing low-dose effects. Thus, a need for developing alternatives to BPA …

The first edition of Bioanalytical Tools in Water Quality Assessment was released in 2012.
The field has exploded since and the second edition updates and reviews the application of …

A set of nine in vitro cellular bioassays indicative of different stages of the cellular toxicity
pathway was applied to 50 disinfection by-products (DBPs) to obtain a better understanding …

In 2008 we published recommendations on chemicals that would be appropriate to evaluate
the sensitivity and specificity of new/modified mammalian cell genotoxicity tests, in particular …

The assessment of genotoxicity represents an essential component of the safety assessment
of all types of substances. Several in vitro tests are available at different stages of …

Micropollutants present in the effluent of wastewater treatment plants (WWTPs) after
biological treatment are largely eliminated by effective advanced technologies such as …

Wastewaters contain complex mixtures of chemicals, which can cause adverse toxic effects
in the receiving environment. In the present study, the toxicity removal during wastewater …