Almost half of all preterm births are caused or triggered by an inflammatory process at the
feto-maternal interface resulting in preterm labor or rupture of membranes with or without …

In the vascular system, the endothelial surface layer (ESL) as the inner surface of blood
vessels affects mechanotransduction, vascular permeability, rheology, thrombogenesis, and …

Macrophage phagocytosis of particles and pathogens is an essential aspect of innate host
defense. Phagocytic function requires cytoskeletal rearrangements that depend on the …

Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor
superfamily that regulate the expression of genes related to lipid and glucose metabolism …

Respiratory diseases are frequently characterised by epithelial injury, airway inflammation,
defective tissue repair, and airway remodelling. This may occur in a subacute or chronic …

Inflammatory diseases are often characterised by excessive neutrophil infiltration from the
blood stream to the site of inflammation, which damages healthy tissue and prevents …

Airborne pathogens and environmental stimuli evoke immune responses in the lung. It is
critical to health that these responses be controlled to prevent tissue damage and the …

Implantation of biomaterials or devices into soft tissue often leads to the development of the
foreign body response (FBR), an inflammatory condition that can cause implant failure …

Mechanical cell–matrix interactions can drive the innate immune responses to infection;
however, the molecular underpinnings of these responses remain elusive. This study was …

Lungs are the most vascular part of humans, accepting the totality of cardiac output in a
volume much smaller than the body itself. Due to this cardiac output, the lung …