[HTML][HTML] NK cell infiltration is associated with improved overall survival in solid cancers: A systematic review and meta-analysis

S Nersesian, SL Schwartz, SR Grantham… - Translational …, 2021 - Elsevier
The immune landscape of a tumor is highly connected to patient prognosis and response to
treatment, but little is known about how natural killer (NK) cells predict overall survival (OS) …

Targeting oral tumor microenvironment for effective therapy

HS Budi, B Farhood - Cancer Cell International, 2023 - Springer
Oral cancers are among the common head and neck malignancies. Different anticancer
therapy modalities such as chemotherapy, immunotherapy, radiation therapy, and also …

Natural killer cell-related prognosis signature characterizes immune landscape and predicts prognosis of HNSCC

H Chi, X Xie, Y Yan, G Peng, DF Strohmer… - Frontiers in …, 2022 - frontiersin.org
Background Head and neck squamous cell carcinoma (HNSCC), the most common head
and neck cancer, is highly aggressive and heterogeneous, resulting in variable prognoses …

Tumor-infiltrating lymphocytes in head and neck cancer: ready for prime time?

A Almangush, S De Keukeleire, S Rottey, L Ferdinande… - Cancers, 2022 - mdpi.com
Simple Summary The immune response has been shown to be a promising indicator to
predict the clinical behavior of many cancers, including head and neck cancer. Tumor …

Prognostic potential of tumor-infiltrating immune cells in resectable oral squamous cell carcinoma

A Caruntu, L Moraru, M Lupu, F Vasilescu… - Cancers, 2021 - mdpi.com
Simple Summary Oral cancer is a common malignancy with high morbidity and mortality.
Tumor-infiltrating immune cells play key roles in its pathogenesis, influencing tumor …

Immune deserts in head and neck squamous cell carcinoma: A review of challenges and opportunities for modulating the tumor immune microenvironment

JL Farlow, JC Brenner, YL Lei, SB Chinn - Oral oncology, 2021 - Elsevier
Immunotherapy revolutionized cancer treatment but has yet to elicit durable responses in the
majority of patients with head and neck squamous cell carcinoma (HNSCC). HNSCC is …

Impaired intratumoral natural killer cell function in head and neck carcinoma

D Mele, G Pessino, G Trisolini, A Luchena… - Frontiers in …, 2022 - frontiersin.org
Natural killer (NK) cells are emerging as unique players in the immune response against
cancer; however, only limited data are available on tumor infiltrating NK cells in head and …

Integrated analysis of single-cell and bulk RNA-sequencing reveals a novel signature based on NK cell marker genes to predict prognosis and immunotherapy …

JR Sun, CF Kong, YX Ye, Q Wang, XK Qu, LQ Jia… - Scientific Reports, 2024 - nature.com
Natural killer (NK) cells play essential roles in the tumor development, diagnosis, and
prognosis of tumors. In this study, we aimed to establish a reliable signature based on …

Role of adenoviruses in cancer therapy

ST Tseha - Frontiers in Oncology, 2022 - frontiersin.org
Cancer is one of the leading causes of death in the world, which is the second after heart
diseases. Adenoviruses (Ads) have become the promise of new therapeutic strategy for …

The 'danse macabre'—neutrophils the interactive partner affecting oral cancer outcomes

S Hadjigol, BA Shah, NM O'Brien-Simpson - Frontiers in Immunology, 2022 - frontiersin.org
Over the past few decades, tremendous advances in the prevention, diagnosis, and
treatment of cancer have taken place. However for head and neck cancers, including oral …