A comprehensive account on recent progress in pharmacological activities of benzimidazole derivatives
Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest
among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole …
among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole …
Aminobenzimidazoles and Structural Isomers as Templates for Dual‐Acting Butyrylcholinesterase Inhibitors and hCB2R Ligands To Combat Neurodegenerative …
D Dolles, M Nimczick, M Scheiner, J Ramler… - …, 2016 - Wiley Online Library
A pharmacophore model for butyrylcholinesterase (BChE) inhibitors was applied to a human
cannabinoid subtype 2 receptor (hCB2R) agonist and verified it as a first‐generation lead for …
cannabinoid subtype 2 receptor (hCB2R) agonist and verified it as a first‐generation lead for …
Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid …
J Romero-Parra, J Mella-Raipán, V Palmieri… - European Journal of …, 2016 - Elsevier
Herein we report the design, synthesis, bioinformatic and biological studies of
benzimidazole and benzothiophene derivatives as new cannabinoid receptor ligands. To …
benzimidazole and benzothiophene derivatives as new cannabinoid receptor ligands. To …
Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor
J Romero-Parra, H Chung, RA Tapia… - European Journal of …, 2017 - Elsevier
The preceding years have brought an exponential increase in our understanding of the
endocannabinoid system (ECS), including the knowledge of CB1 and CB2 cannabinoid …
endocannabinoid system (ECS), including the knowledge of CB1 and CB2 cannabinoid …
Impact of Cannabinoid Receptors in the Design of Therapeutic Agents against Human Ailments
The Cannabinoid (CB) signalling cascade is widely located in the human body and is
associated with several pathophysiological processes. The endocannabinoid system …
associated with several pathophysiological processes. The endocannabinoid system …
Motifs in Natural Products as Useful Scaffolds to Obtain Novel Benzo[d]imidazole-Based Cannabinoid Type 2 (CB2) Receptor Agonists
AYH Cho, H Chung, J Romero-Parra, P Kumar… - International Journal of …, 2023 - mdpi.com
The endocannabinoid system (ECS) constitutes a broad-spectrum modulator of homeostasis
in mammals, providing therapeutic opportunities for several pathologies. Its two main …
in mammals, providing therapeutic opportunities for several pathologies. Its two main …
Computational Modeling of Non-active Functional States of the Cannabinoid Receptor 1 and its Ligands
AO Aderibigbe - 2021 - search.proquest.com
Abstract The cannabinoid receptor 1 (CB1) is a class A G-protein coupled receptor that is
implicated in a variety of physiological processes, such as energy homeostasis, appetite …
implicated in a variety of physiological processes, such as energy homeostasis, appetite …
Búsqueda De Moduladores Del Sistema Endocannabinoide: Síntesis Y Evaluación Biológica De Carbamoilos De Anillos Benzoimidazólicos, Diseñados Por …
RAE Valderrama - 2021 - search.proquest.com
Desde tiempos remotos, la Cannabis ha sido utilizada tanto por sus acciones medicinales
como por sus efectos recreacionales. En la actualidad, hay un sin número de estudios …
como por sus efectos recreacionales. En la actualidad, hay un sin número de estudios …
[引用][C] El patrimonio en la recuperación de Santiago nor-poniente: Barrio Portales
JI Tapia - 2007 - Pontificia Universidad Católica de …