Extracellular DNA traps: Origin, function and implications for anti-cancer therapies

M Mamtimin, A Pinarci, C Han, A Braun… - Frontiers in …, 2022 - frontiersin.org
Extracellular DNA may serve as marker in liquid biopsies to determine individual diagnosis
and prognosis in cancer patients. Cell death or active release from various cell types …

Significance of mast cell formed extracellular traps in microbial defense

D Elieh Ali Komi, WM Kuebler - Clinical reviews in allergy & immunology, 2022 - Springer
Mast cells (MCs) are critically involved in microbial defense by releasing antimicrobial
peptides (such as cathelicidin LL-37 and defensins) and phagocytosis of microbes. In past …

Diagnostic and prognostic value of monocyte distribution width in sepsis

J Wu, L Li, J Luo - Journal of Inflammation Research, 2022 - Taylor & Francis
Monocyte distribution width (MDW) is a blood monocyte morphological parameter that can
be easily detected by an automated hemocyte analyzer and can provide clinicians with …

Multiple origins of extracellular DNA traps

E Ramos-Martínez, L Hernández-González… - Frontiers in …, 2021 - frontiersin.org
Extracellular DNA traps (ETs) are evolutionarily conserved antimicrobial mechanisms
present in protozoa, plants, and animals. In this review, we compare their similarities in …

Oxidative stress as an underlying mechanism of bacteria-inflicted damage to male gametes

E Tvrdá, F Benko, M Ďuračka - Oxygen, 2022 - mdpi.com
Bacterial infestation of the male reproductive system with subsequent effects of bacteria on
the structural integrity and functional activity of male gametes has become a significant factor …

Effect of different sperm populations on neutrophils extracellular traps (NETs) formation in cattle

R Rivera-Concha, C Moya, M León, P Uribe… - Research in Veterinary …, 2023 - Elsevier
In cattle, clinical and subclinical inflammation in the bovine female reproductive tract (FRT)
significantly reduces fertility. PMN participate in this FRT-associated inflammation by …

[HTML][HTML] Novel perception of neutrophil extracellular traps in gouty inflammation

H Tan, Z Li, S Zhang, J Zhang, E Jia - International immunopharmacology, 2023 - Elsevier
The self-limiting nature of the inflammatory flare is a feature of gout. The effects of neutrophil
extracellular traps (NETs) on gout have remarkably attracted researchers' attention …

Bovine sperm samples induce different NET phenotypes in a NADPH oxidase-, PAD4-, and Ca++-dependent process

T Fichtner, F Kotarski, U Gärtner… - Biology of …, 2020 - academic.oup.com
Deposition of sperm during artificial insemination in the bovine female reproductive tract
results in early host innate immune reactions of polymorphonuclear neutrophils (PMNs) …

Sperm induce macrophage extracellular trap formation via phagocytosis-dependent mechanism

C Lu, Z Wu, H Gao, H Li, R Deng, N Luo… - Biology of …, 2023 - academic.oup.com
Infertility is a public health concern worldwide. Asthenozoospermia is a common cause of
male infertility and is characterized by decreased motility. Sperm motility ensures that sperm …

Bacteriospermia–A formidable player in male subfertility

E Tvrdá, M Ďuračka, F Benko, N Lukáč - Open Life Sciences, 2022 - degruyter.com
Bacterial colonization of male reproductive tissues, cells, and fluids, and the subsequent
impact of bacteria on the sperm architecture, activity, and fertilizing potential, has recently …