Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …

Malaria is the most deadly parasitic disease, affecting hundreds of millions of people
worldwide. Malaria parasites have been associated with their hosts for millions of years …

Type I interferons (IFN-Is) are important cytokines playing critical roles in various infections,
autoimmune diseases, and cancer. Studies have also shown that IFN-Is exhibit …

Infection by malaria parasites triggers dynamic immune responses leading to diverse
symptoms and pathologies; however, the molecular mechanisms responsible for these …

Recent advances in malaria genetics and genomics have transformed many aspects of
malaria research in areas of molecular evolution, epidemiology, transmission, host–parasite …

For many years, the role of interferon (IFN)-I has been characterized primarily in the context
of viral infections. However, regulatory functions mediated by IFN-I have also been …

Malaria infection induces complex and diverse immune responses. To elucidate the
mechanisms underlying host–parasite interaction, we performed a genetic screen during …

DNA that gains access to the cytoplasm generally serves as a danger signal for the hosts.
An emerging paradigm for responding to cytosolic DNA s centres on the endoplasmic …

Olfactory receptors (Olfr) are G protein–coupled receptors that are normally expressed on
olfactory sensory neurons to detect volatile chemicals or odorants. Interestingly, many Olfrs …

Innate immune response plays a critical role in controlling invading pathogens, but such an
immune response must be tightly regulated. Insufficient or overactivated immune responses …