Immune cell-mediated features of non-alcoholic steatohepatitis
T Huby, EL Gautier - Nature reviews immunology, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) includes a range of hepatic manifestations,
starting with liver steatosis and potentially evolving towards non-alcoholic steatohepatitis …
starting with liver steatosis and potentially evolving towards non-alcoholic steatohepatitis …
Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity
Non-alcoholic fatty liver disease (NAFLD) has emerged pandemically across the globe and
particularly affects patients with obesity and type 2 diabetes. NAFLD is a complex systemic …
particularly affects patients with obesity and type 2 diabetes. NAFLD is a complex systemic …
Autophagy in liver diseases: a review
The liver is a highly dynamic metabolic organ that plays critical roles in plasma protein
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …
synthesis, gluconeogenesis and glycogen storage, cholesterol metabolism and bile acid …
[HTML][HTML] Cholesterol-induced toxicity: An integrated view of the role of cholesterol in multiple diseases
Y Song, J Liu, K Zhao, L Gao, J Zhao - Cell metabolism, 2021 - cell.com
High levels of cholesterol are generally considered to be associated with atherosclerosis. In
the past two decades, however, a number of studies have shown that excess cholesterol …
the past two decades, however, a number of studies have shown that excess cholesterol …
Mechanisms of fibrosis development in nonalcoholic steatohepatitis
Nonalcoholic fatty liver disease is the most prevalent liver disease worldwide, affecting 20%–
25% of the adult population. In 25% of patients, nonalcoholic fatty liver disease progresses …
25% of the adult population. In 25% of patients, nonalcoholic fatty liver disease progresses …
Triggering and resolution of inflammation in NASH
S Schuster, D Cabrera, M Arrese… - Nature reviews …, 2018 - nature.com
Nonalcoholic steatohepatitis (NASH) is considered the progressive form of nonalcoholic fatty
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …
liver disease (NAFLD) and is characterized by liver steatosis, inflammation, hepatocellular …
Changes in glutathione content in liver diseases: an update
Glutathione (GSH), a tripeptide particularly concentrated in the liver, is the most important
thiol reducing agent involved in the modulation of redox processes. It has also been …
thiol reducing agent involved in the modulation of redox processes. It has also been …
[PDF][PDF] Role of cholesterol‐associated steatohepatitis in the development of NASH
CL Horn, AL Morales, C Savard… - Hepatology …, 2022 - Wiley Online Library
The rising prevalence of nonalcoholic fatty liver disease (NAFLD) and NAFLD‐related
cirrhosis in the United States and globally highlights the need to better understand the …
cirrhosis in the United States and globally highlights the need to better understand the …
ER stress drives lipogenesis and steatohepatitis via caspase-2 activation of S1P
JY Kim, R Garcia-Carbonell, S Yamachika, P Zhao… - Cell, 2018 - cell.com
Nonalcoholic fatty liver disease (NAFLD) progresses to nonalcoholic steatohepatitis (NASH)
in response to elevated endoplasmic reticulum (ER) stress. Whereas the onset of simple …
in response to elevated endoplasmic reticulum (ER) stress. Whereas the onset of simple …
Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment
ME Ertunc, GS Hotamisligil - Journal of lipid research, 2016 - ASBMB
Lipids encompass a wide variety of molecules such as fatty acids, sterols, phospholipids,
and triglycerides. These molecules represent a highly efficient energy resource and can act …
and triglycerides. These molecules represent a highly efficient energy resource and can act …