In ARDS patients, the change from supine to prone position generates a more even
distribution of the gas–tissue ratios along the dependent–nondependent axis and a more …

Prone positioning was first proposed in the 1970s as a method to improve gas exchange in
ARDS. Subsequent observations of dramatic improvement in oxygenation with simple …

This review provides an overview of the relationship between ventilation/perfusion ratios
and gas exchange in the lung, emphasising basic concepts and relating them to clinical …

Background Very severe chronic obstructive pulmonary disease causes cor pulmonale with
elevated pulmonary vascular resistance and secondary reductions in left ventricular filling …

Journal of Addiction Medicine; serving on the editorial board of Journal of Addictive
Diseases and Addiction Science & Clinical Practice; serving as an expert witness in …

Prone positioning of patients during anaesthesia is required to provide operative access for
a wide variety of surgical procedures. It is associated with predictable changes in physiology …

Blood flow (BF) increases with increasing exercise intensity in skeletal, respiratory, and
cardiac muscle. In humans during maximal exercise intensities, 85% to 90% of total cardiac …

The mechanism by which oxygenation improves when patients with ARDS are turned from
supine to prone position is not known. From results of our previous studies we reasoned that …

The prone position improves gas exchange in many patients with ARDS. Animal studies
have indicated that turning prone restores ventilation to dorsal lung regions without …

In the absence of effective targeted therapies for COVID-19, optimisation of supportive care
is essential. Lung injury with features of acute respiratory distress syndrome (ARDS) …