Monitoring synaptic pathology in Alzheimer's disease through fluid and PET imaging biomarkers: a comprehensive review and future perspectives
Alzheimer's disease (AD) is currently constrained by limited clinical treatment options. The
initial pathophysiological event, which can be traced back to decades before the clinical …
initial pathophysiological event, which can be traced back to decades before the clinical …
Alpha-synuclein in peripheral tissues as a possible marker for neurological diseases and other medical conditions
FJ Jiménez-Jiménez, H Alonso-Navarro… - Biomolecules, 2023 - mdpi.com
The possible usefulness of alpha-synuclein (aSyn) determinations in peripheral tissues
(blood cells, salivary gland biopsies, olfactory mucosa, digestive tract, skin) and in biological …
(blood cells, salivary gland biopsies, olfactory mucosa, digestive tract, skin) and in biological …
Co-aggregation of α-synuclein with amyloid-β stabilizes β-sheet-rich oligomers and enhances the formation of β-barrels
Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common
neurodegenerative diseases with markedly different pathological features of β-amyloid (Aβ) …
neurodegenerative diseases with markedly different pathological features of β-amyloid (Aβ) …
Aggregation-resistant alpha-synuclein tetramers are reduced in the blood of Parkinson's patients
L de Boni, A Wallis, A Hays Watson… - EMBO Molecular …, 2024 - embopress.org
Synucleinopathies such as Parkinson's disease (PD) are defined by the accumulation and
aggregation of the α-synuclein protein in neurons, glia and other tissues. We have …
aggregation of the α-synuclein protein in neurons, glia and other tissues. We have …
Exploring Epithelial–Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes
V Cela, E Malacarne, MER Obino, I Marzi, F Papini… - Biomedicines, 2021 - mdpi.com
Endometriosis (EMS) pathogenesis has been related to the release of inflammatory
mediators in peritoneal fluid, creating an altered microenvironment that leads to low-grade …
mediators in peritoneal fluid, creating an altered microenvironment that leads to low-grade …
α-synuclein as an emerging pathophysiological biomarker of Alzheimer's disease
MF Beatino, C De Luca, N Campese… - Expert Review of …, 2022 - Taylor & Francis
Introduction α-syn aggregates represent the pathological hallmark of synucleinopathies as
well as a frequent copathology (almost 1/3 of cases) in AD. Recent research indicates a …
well as a frequent copathology (almost 1/3 of cases) in AD. Recent research indicates a …
Reconsidering red blood cells as the diagnostic potential for neurodegenerative disorders
Abstract Background Red blood cells (RBCs) are usually considered simple cells and
transporters of gases to tissues. Hypothesis However, recent research has suggested that …
transporters of gases to tissues. Hypothesis However, recent research has suggested that …
LC–MS/MS assay for the investigation of acetylated Alpha-synuclein in serum from postmortem Alzheimer's disease pathology
K Uchida, K Morikawa, Y Muguruma… - … of Chromatography B, 2021 - Elsevier
Abstract Alpha-synuclein (α-Syn), a neuronal protein, has been linked to the inflammation
and development of neurodegenerative diseases. In a number of neurodegenerations, α …
and development of neurodegenerative diseases. In a number of neurodegenerations, α …