The trillions of cells in the human body can be viewed as elementary but essential biological
units that achieve different body states, but the low resolution of previous cell isolation and …

Automatic and accurate classification of apoptosis, or programmed cell death, will facilitate
cell biology research. The state-of-the-art approaches in apoptosis classification use deep …

Multiple factors in the design of a chimeric antigen receptor (CAR) influence CAR T-cell
activity, with costimulatory signals being a key component. Yet, the impact of costimulatory …

Chimeric antigen receptor (CAR) T cell show promise in cancer treatments, but their
mechanism of action is not well understood. Decoding the mechanisms used by individual T …

Background Adoptive cell therapy based on the infusion of chimeric antigen receptor (CAR)
T cells has shown remarkable efficacy for the treatment of hematologic malignancies. The …

Time lapse microscopy is essential for quantifying the dynamics of cells, subcellular
organelles and biomolecules. Biologists use different fluorescent tags to label and track the …

Motivation Reliable label-free methods are needed for detecting and profiling apoptotic
events in time-lapse cell–cell interaction assays. Prior studies relied on fluorescent markers …

Aiming at the problems of large data volume, long calculation time, and information
feedback speed in traditional virtual augmented reality-based scenes, this paper constructed …

Accurate classification of apoptosis plays an important role in cell biology research. There
are many state-of-the-art approaches which use deep CNNs to perform the apoptosis …

Adoptive chimeric antigen receptor T-cell (CAR-T) therapy is transformative and approved
for hematologic malignancies, as well being developed for treatment of solid tumors …