Alzheimer's disease (AD) affects various brain cell types, including astrocytes, which are the
most abundant cell types in the central nervous system (CNS). Astrocytes not only provide …

Amyloid PET imaging has been crucial for detecting the accumulation of amyloid beta (Aβ)
deposits in the brain and to study Alzheimer's disease (AD). We performed a genome-wide …

Alzheimer's disease (AD) is the most common neurodegenerative dementia with multi‐
layered complexity in its molecular etiology. Multiple omics‐based approaches, such as …

Introduction Alzheimer's disease (AD) is a complex neurodegenerative disease with high
heritability. Compared to autosomes, a higher proportion of disorder-associated genes on X …

The transcription factor regulatory factor X 7 (RFX7) has been identified as a tumor
suppressor that is recurrently mutated in lymphoid cancers and appears to be dysregulated …

While previous research has shown the potential links between taste perception pathways
and brain-related conditions, the area involving Alzheimer's disease remains incompletely …

Shortening of telomere length (TL) is correlated with many age-related disorders and is a
hallmark of biological aging. This study used proteome-wide Mendelian randomization to …

Background Alzheimer's disease (AD) is a heritable neurodegenerative disease whose long
asymptomatic phase makes the early diagnosis of it pivotal. Blood U-p53 has recently …

New “omic” technologies are revealing shared and distinct biological pathways within and
across neurodegenerative diseases (NDDs), allowing a better understanding of …

Background Tau, a microtubule-associated protein extensively distributed within the central
nervous system (CNS), exhibits close associations with various neurodegenerative …