Tools and methods for circular dichroism spectroscopy of proteins: a tutorial review

AJ Miles, RW Janes, BA Wallace - Chemical Society Reviews, 2021 - pubs.rsc.org
Circular dichroism (CD) spectroscopy is a widely-used method in biochemistry, structural
biology and pharmaceutical chemistry. More than 24 000 papers published in the past …

Electronic circular dichroism spectroscopy of proteins

DM Rogers, SB Jasim, NT Dyer, F Auvray, M Réfrégiers… - Chem, 2019 - cell.com
Electronic circular dichroism (CD) spectroscopy is an important tool for the elucidation of
biomolecular structure. This review describes the latest progress and developments in …

DichroWeb, a website for calculating protein secondary structure from circular dichroism spectroscopic data

AJ Miles, SG Ramalli, BA Wallace - Protein Science, 2022 - Wiley Online Library
Circular dichroism (CD) spectroscopy is a widely‐used method for characterizing the
secondary structures of proteins. The well‐established and highly used analysis website …

A single sulfatase is required to access colonic mucin by a gut bacterium

AS Luis, C Jin, GV Pereira, RWP Glowacki, SR Gugel… - Nature, 2021 - nature.com
Humans have co-evolved with a dense community of microbial symbionts that inhabit the
lower intestine. In the colon, secreted mucus creates a barrier that separates these …

BeStSel: webserver for secondary structure and fold prediction for protein CD spectroscopy

A Micsonai, E Moussong, F Wien, E Boros… - Nucleic Acids …, 2022 - academic.oup.com
Circular dichroism (CD) spectroscopy is widely used to characterize the secondary structure
composition of proteins. To derive accurate and detailed structural information from the CD …

Score-based generative modeling for de novo protein design

JS Lee, J Kim, PM Kim - Nature Computational Science, 2023 - nature.com
The generation of de novo protein structures with predefined functions and properties
remains a challenging problem in protein design. Diffusion models, also known as score …

Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19

M Charnley, S Islam, GK Bindra, J Engwirda… - Nature …, 2022 - nature.com
COVID-19 is primarily known as a respiratory disease caused by SARS-CoV-2. However,
neurological symptoms such as memory loss, sensory confusion, severe headaches, and …

Investigation on the effect of fluorescence quenching of calf thymus DNA by piperine: caspase activation in the human breast cancer cell line studies

S Rezaei, HS Meftah, Y Ebtehajpour… - DNA and Cell …, 2024 - liebertpub.com
In this study, we determined the interaction of piperine and calf thymus DNA (ct DNA) in Tris-
HCl buffer solution at pH= 6.8 and also evaluated the binding mechanism through the data …

Evaluation of the binding effect and cytotoxicity assay of 2‐Ethyl‐5‐(4‐methylphenyl) pyramido pyrazole ophthalazine trione on calf thymus DNA: spectroscopic …

N Marjani, M Dareini, M Asadzade‐Lotfabad… - …, 2022 - Wiley Online Library
With advances in new drug therapies, it is essential to understand the interactions between
drugs and target molecules. In this study, we applied multiple spectroscopic techniques …

Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses

F Geiger, J Acker, G Papa, X Wang, WE Arter… - The EMBO …, 2021 - embopress.org
RNA viruses induce the formation of subcellular organelles that provide microenvironments
conducive to their replication. Here we show that replication factories of rotaviruses …