Clinical pancreatic islet transplantation

AMJ Shapiro, M Pokrywczynska… - Nature Reviews …, 2017 - nature.com
Clinical pancreatic islet transplantation can be considered one of the safest and least
invasive transplant procedures. Remarkable progress has occurred in both the technical …

[HTML][HTML] Guidelines for the understanding and management of pain in chronic pancreatitis

AM Drewes, SAW Bouwense, CM Campbell… - Pancreatology, 2017 - Elsevier
Abdominal pain is the foremost complication of chronic pancreatitis (CP). Pain can be
related to recurrent or chronic inflammation, local complications or neurogenic mechanisms …

ACG clinical guideline: chronic pancreatitis

TB Gardner, DG Adler, CE Forsmark… - Official journal of the …, 2020 - journals.lww.com
Chronic pancreatitis (CP) is historically defined as an irreversible inflammatory condition of
the pancreas leading to varying degrees of exocrine and endocrine dysfunction. Recently …

How durable is total pancreatectomy and intraportal islet cell transplantation for treatment of chronic pancreatitis?

MD Bellin, GJ Beilman, DER Sutherland, H Ali… - Journal of the American …, 2019 - Elsevier
Background A total pancreatectomy and intraportal islet cell autotransplant (TPIAT) is
increasingly being offered to patients with chronic pancreatitis (CP). The benefits include …

Controversies on the endoscopic and surgical management of pain in patients with chronic pancreatitis: pros and cons!

AM Drewes, MA Kempeneers, DK Andersen… - Gut, 2019 - gut.bmj.com
Pain is the dominating symptom of chronic pancreatitis (CP) causing impairment of quality of
life, decreased activity, unemployment and major healthcare costs. 1 Opinions differ on the …

The role of total pancreatectomy with islet autotransplantation in the treatment of chronic pancreatitis: A report from the International Consensus Guidelines in chronic …

M Abu-El-Haija, T Anazawa, GJ Beilman, MG Besselink… - Pancreatology, 2020 - Elsevier
Background Advances in our understanding of total pancreatectomy with islet
autotransplantation (TPIAT) have been made. We aimed to define indications and outcomes …

Are there still indications for total pancreatectomy?

M Del Chiaro, E Rangelova, R Segersvärd, U Arnelo - Updates in surgery, 2016 - Springer
Total pancreatectomy is associated with short-and long-term high complication rate and
without evidence of oncologic advantages. Several metabolic consequences are co-related …

A multicenter study of total pancreatectomy with islet autotransplantation (TPIAT): POST (Prospective Observational Study of TPIAT)

MD Bellin, M Abu-El-Haija, K Morgan, D Adams… - Pancreatology, 2018 - Elsevier
Background/objectives Total pancreatectomy with islet autotransplantation (TPIAT) is
considered for managing chronic pancreatitis in selected patients when medical and …

Surgical approach and short-term outcomes in adults and children undergoing total pancreatectomy with islet autotransplantation: A report from the Prospective …

JD Nathan, Y Yang, A Eaton, P Witkowski, M Wijkstrom… - Pancreatology, 2022 - Elsevier
Background Total pancreatectomy with islet autotransplantation (TPIAT) is a viable option for
treating debilitating recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) in …

Single-cell sequencing unveils distinct immune microenvironments with CCR6-CCL20 crosstalk in human chronic pancreatitis

B Lee, H Namkoong, Y Yang, H Huang, D Heller… - Gut, 2022 - gut.bmj.com
Objective Chronic pancreatitis (CP) is a potentially fatal disease of the exocrine pancreas,
with no specific or effective approved therapies. Due to difficulty in accessing pancreas …