Long non-coding RNAs (lncRNAs) are the novel class of transcripts involved in
transcriptional, post-transcriptional, translational, and post-translational regulation of …

Angiogenesis is a key process in organ and tissue morphogenesis, as well as growth during
human development, and is coordinated by pro-and anti-angiogenic factors. When this …

Circular RNAs (circRNAs) are expressed at high levels in the brain and are involved in
various central nervous system diseases. However, the potential role of circRNAs in …

Background Brain microvascular endothelial cell (BMEC) injury can affect neuronal survival
by modulating immune responses through the microenvironment. Exosomes are important …

Stroke is a devastating medical condition with no treatment to hasten recovery. Its abrupt
nature results in cataclysmic changes in the affected tissues. Resident cells fail to cope with …

Stroke is a major contributor to mortality and impairment on a global scale, with few effective
treatments available. Aberrant expression of various non-coding RNAs (ncRNAs) has been …

Background Hypoxia following ischemic stroke is a common cause of brain insults. Mounting
evidence suggests that long non-coding RNAs (lncRNAs) play a vital role in regulating …

Endoplasmic reticulum stress (ERS) contributes to the pathogenesis of myocardial
ischemia/reperfusion injury and myocardial infarction (MI). Long non-coding RNAs …

Ischemic stroke (IS) is a disease that is characterized by high mortality and disability. Recent
studies have shown that LncRNA-mediated competing endogenous RNA (ceRNA) networks …

The current work was developed to explore the functions and possible mechanism of PRG4
in cardiac hypertrophy and heart failure. Ang II-stimulated H9c2 cells and AC16 cells were …