State-of-the-art dermatophyte infections: epidemiology aspects, pathophysiology, and resistance mechanisms
The burden of fungal infections is not widely appreciated. Although these infections are
responsible for over one million deaths annually, it is estimated that one billion people are …
responsible for over one million deaths annually, it is estimated that one billion people are …
Pathogenesis of dermatophytosis: sensing the host tissue
Abstract The genera Trichophyton, Microsporum, and Epidermophyton include filamentous
fungi that cause dermatophytosis, a superficial infection of the skin, stratum corneum, nail …
fungi that cause dermatophytosis, a superficial infection of the skin, stratum corneum, nail …
Metabolomic analysis of Trichophyton rubrum and Microsporum canis during keratin degradation
A Ciesielska, A Kawa, K Kanarek, A Soboń… - Scientific reports, 2021 - nature.com
Keratin is important and needed for the growth of dermatophytes in the host tissue. In turn,
the ability to invade keratinised tissues is defined as a pivotal virulence attribute of this group …
the ability to invade keratinised tissues is defined as a pivotal virulence attribute of this group …
In vitro and ex vivo infection models help assess the molecular aspects of the interaction of Trichophyton rubrum with the host milieu
Dermatophytes are fungal pathogens that cause cutaneous infections such as
onychomycosis and athlete's foot in both healthy and immunocompromised patients …
onychomycosis and athlete's foot in both healthy and immunocompromised patients …
HacA Governs Virulence Traits and Adaptive Stress Responses in Trichophyton rubrum
TA Bitencourt, EAS Lang, PR Sanches… - Frontiers in …, 2020 - frontiersin.org
The ability of fungi to sense environmental stressors and appropriately respond is linked to
secretory system functions. The dermatophyte infection process depends on an orchestrated …
secretory system functions. The dermatophyte infection process depends on an orchestrated …
Relevance of Nutrient-Sensing in the Pathogenesis of Trichophyton rubrum and Trichophyton interdigitale
The growth and development of organisms depend on nutrient availability. Dermatophytes
must sense nutrient levels and adapt to the host environment to colonize human and animal …
must sense nutrient levels and adapt to the host environment to colonize human and animal …
Ambient pH sensing in filamentous fungi: pitfalls in elucidating regulatory hierarchical signaling networks
In this article, the experiments used to construct the ambient pH‐signaling network involved
in the secretion of enzymes by filamentous fungi have been reviewed, focusing on the …
in the secretion of enzymes by filamentous fungi have been reviewed, focusing on the …
A Dual-Plasmid-Based CRISPR/Cas9-Mediated Strategy Enables Targeted Editing of pH Regulatory Gene pacC in a Clinical Isolate of Trichophyton rubrum
Trichophyton rubrum is the most prevalent causative agent responsible for 80–90% of all
known superficial fungal infections in humans, worldwide. Limited available methods for …
known superficial fungal infections in humans, worldwide. Limited available methods for …
The PAC-3 transcription factor critically regulates phenotype-associated genes in Neurospora crassa
MP Martins, NM Martinez-Rossi… - … and Molecular Biology, 2020 - SciELO Brasil
Transcription factors play an important role in fungal environmental adaptive process by
promoting adjustment to challenging stimuli via gene modulation and activation of signaling …
promoting adjustment to challenging stimuli via gene modulation and activation of signaling …
Expressão, regulação e funcionalidade de genes HSPs no dermatófito Trichophyton rubrum
TR Jacob - 2014 - teses.usp.br
O dermatófito Trichophyton rubrum é um fungo filamentoso, queratinofílico e antropofílico,
sendo o principal agente etiológico de micoses cutâneas em humanos. Sua distribuição …
sendo o principal agente etiológico de micoses cutâneas em humanos. Sua distribuição …