Sensorineural hearing loss (SNHL) is characterized by a compromised cochlear perception
of sound waves. Major risk factors for SNHL include genetic mutations, exposure to noise …

ER network formation depends on membrane fusion by the atlastin (ATL) GTPase. In
humans, three paralogs are differentially expressed with divergent N-and C-terminal …

Endoplasmic reticulum (ER) tubules are interconnected by three-way junctions, resulting in
the formation of a tubular ER network. Lunapark (Lnp) localizes to and stabilizes the three …

The peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor
abundantly expressed in the nonalcoholic fatty liver disease (NAFLD). In this study, we …

As the auditory and balance receptor cells in the inner ear, hair cells are responsible for
converting mechanical stimuli into electrical signals, a process referred to as mechano …

Cancer stem cells (CSC) play a pivotal role in cancer metastasis and resistance to therapy.
Previously, we compared the phosphoproteomes of breast cancer stem cells (BCSCs) …

Immunotherapy with immune checkpoint inhibitors has largely improved survival of
melanoma patients. However, many patients still do not benefit from so far developed …

The reticular network of the endoplasmic reticulum (ER) is formed by connecting ER tubules
through three-way junctions and undergoes constant remodeling through formation and loss …