Soft‐tissue sarcoma in adults: an update on the current state of histiotype‐specific management in an era of personalized medicine

AC Gamboa, A Gronchi… - CA: a cancer journal for …, 2020 - Wiley Online Library
Soft‐tissue sarcomas (STS) are rare tumors that account for 1% of all adult malignancies,
with over 100 different histologic subtypes occurring predominately in the trunk, extremity …

Neoadjuvant chemotherapy in soft tissue sarcomas: latest evidence and clinical implications

S Pasquali, A Gronchi - Therapeutic advances in medical …, 2017 - journals.sagepub.com
Soft tissue sarcomas are a rare and multifaceted group of solid tumours. Neoadjuvant
chemotherapy is increasingly used to limit loss of function after wide surgical excision with …

Neoadjuvant chemotherapy in high-risk soft tissue sarcomas: final results of a randomized trial from Italian (ISG), Spanish (GEIS), French (FSG), and Polish (PSG) …

A Gronchi, E Palmerini, V Quagliuolo… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To determine whether the administration of histology-tailored neoadjuvant
chemotherapy (HT) was superior to the administration of standard anthracycline plus …

The effect of the setting of a positive surgical margin in soft tissue sarcoma

PW O'Donnell, AM Griffin, WC Eward, A Sternheim… - Cancer, 2014 - Wiley Online Library
BACKGROUND The objectives of this study were to evaluate the risk of local recurrence and
survival after soft tissue sarcoma (STS) resection with positive margins and to evaluate the …

Margin assessment in soft tissue sarcomas: review of the literature

A Sambri, E Caldari, M Fiore, R Zucchini, C Giannini… - Cancers, 2021 - mdpi.com
Simple Summary Many classifications to assess margins status for soft tissue sarcomas are
reported in the literature. Most of the series are heterogeneous and variable in size, making …

[HTML][HTML] Tenosynovial giant cell tumour/pigmented villonodular synovitis: outcome of 294 patients before the era of kinase inhibitors

E Palmerini, EL Staals, RG Maki, S Pengo… - European Journal of …, 2015 - Elsevier
Background Tenosynovial giant cell tumour/pigmented villonodular synovitis (TGCT/PVNS)
is a benign neoplasm of synovium and tendon sheath. We conducted a retrospective pooled …

[HTML][HTML] Short, full-dose adjuvant chemotherapy (CT) in high-risk adult soft tissue sarcomas (STS): long-term follow-up of a randomized clinical trial from the Italian …

A Gronchi, S Stacchiotti, P Verderio, S Ferrari… - Annals of …, 2016 - Elsevier
The equivalence of a short full-dose regimen of neoadjuvant CT with anthracycline-
ifosfamide compared with standard dosing in localized high-risk soft tissue sarcoma is …

The width of resection margins influences local recurrence in soft tissue sarcoma patients

V Kainhofer, MA Smolle, J Szkandera… - European Journal of …, 2016 - Elsevier
Background Patients with soft tissue sarcoma (STS) being treated following the standardized
guidelines can still not be guaranteed to remain free from local recurrence (LR). A complete …

Primary extremity soft tissue sarcomas: does local control impact survival?

S Bonvalot, A Levy, P Terrier, D Tzanis… - Annals of surgical …, 2017 - Springer
Background The objective of this study was to evaluate the adequate margin in the local
treatment of extremity soft tissue sarcomas (ESTS) and understand the relationship between …

The effect of resection margin on local recurrence and survival in high grade soft tissue sarcoma of the extremities: how far is far enough?

A Bilgeri, A Klein, LH Lindner, S Nachbichler, T Knösel… - Cancers, 2020 - mdpi.com
Simple Summary In soft tissue sarcomas the width of surgical margins after resection
determines the extent of surgery and the function after resection. But how far is really …