The Longitudinal Effect of Diabetes-Associated Variation in TCF7L2 on Islet Function in Humans

M Zeini, MC Laurenti, AM Egan, K Muthusamy… - Diabetes, 2024 - diabetesjournals.org
The T allele at rs7903146 in TCF7L2 increases the rate of conversion from prediabetes to
type 2 diabetes. This has been associated with impaired β-cell function and with defective …

Diabetes-associated Genetic Variation in MTNR1B and Its Effect on Islet Function

M Vella, S Mohan, H Christie, KR Bailey… - Journal of the …, 2024 - academic.oup.com
Context Multiple common genetic variants have been associated with type 2 diabetes, but
the mechanism by which they predispose to diabetes is incompletely understood. One such …

[PDF][PDF] High exposure variance enables candidate biomarker detection in a small EWAS of methylmercury-exposed Peruvian adults

C Weinhouse, L Perez, I Ryde, JM Goodrich… - bioRxiv, 2022 - scholar.archive.org
Background. Methylmercury (MeHg) is an environmental pollutant of global public health
concern. MeHg is associated with 64 immune dysfunction but the underlying mechanisms …

Ассоциация полиморфизмов генов CSK, MTHFR, ACE, ADRA2B, TCF7L2 с дислипидемией среди коренного и некоренного населения Ханты-Мансийского …

ЕВ Корнеева, МИ Воевода, СЕ Семаев… - …, 2023 - ateroskleroz.elpub.ru
Аннотация Рост сердечно-сосудистых заболеваний, сахарного диабета и
метаболического синдрома определяет актуальность ранней диагностики и …