Emerging roles of alternative cleavage and polyadenylation (APA) in human disease
P Dharmalingam, R Mahalingam… - Journal of Cellular …, 2022 - Wiley Online Library
In the messenger RNA (mRNA) maturation process, the 3′‐end of pre‐mRNA is cleaved
and a poly (A) sequence is added, this is an important determinant of mRNA stability and its …
and a poly (A) sequence is added, this is an important determinant of mRNA stability and its …
NUDT21 alters glioma migration through differential alternative polyadenylation of LAMC1
Purpose Gliomas and their surrounding microenvironment constantly interact to promote
tumorigenicity, yet the underlying posttranscriptional regulatory mechanisms that govern this …
tumorigenicity, yet the underlying posttranscriptional regulatory mechanisms that govern this …
Click Chemistry Enables Rapid Amplification of Full-Length Reverse Transcripts for Long-Read Third Generation Sequencing
ES Schönegger, A Crisp, M Müller, J Fertl… - Bioconjugate …, 2022 - ACS Publications
Here we describe the development of a novel click chemistry-based method for the
generation and amplification of full-length cDNA libraries from total RNA, while avoiding the …
generation and amplification of full-length cDNA libraries from total RNA, while avoiding the …
A computational pipeline to infer alternative poly-adenylation from 3′ sequencing data
An increasing number of investigations have established alternative polyadenylation (APA)
as a key mechanism of gene regulation through altering the length of 3′ untranslated …
as a key mechanism of gene regulation through altering the length of 3′ untranslated …