[HTML][HTML] Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction

Y Ma, AJ Mouton, ML Lindsey - Translational Research, 2018 - Elsevier
Macrophages play critical roles in homeostatic maintenance of the myocardium under
normal conditions and in tissue repair after injury. In the steady-state heart, resident cardiac …

Monocyte and macrophage contributions to cardiac remodeling

M Hulsmans, F Sam, M Nahrendorf - Journal of molecular and cellular …, 2016 - Elsevier
The mammalian heart contains a population of resident macrophages that expands in
response to myocardial infarction and hemodynamic stress. This expansion occurs likely …

Infarct in the heart: what's MMP-9 got to do with it?

M Becirovic-Agic, U Chalise, MJ Daseke, S Konfrst… - Biomolecules, 2021 - mdpi.com
Over the past three decades, numerous studies have shown a strong connection between
matrix metalloproteinase 9 (MMP-9) levels and myocardial infarction (MI) mortality and left …

Cardioprotective function of cardiac macrophages

K Fujiu, J Wang, R Nagai - Cardiovascular research, 2014 - academic.oup.com
The heart is composed of several cell types including cardiomyocytes, cardiac fibroblasts,
endothelial, and smooth muscle cells. In addition to these major cell types, cardiac …

Mathematical modeling and bifurcation analysis of pro-and anti-tumor macrophages

Y Shu, J Huang, Y Dong, Y Takeuchi - Applied Mathematical Modelling, 2020 - Elsevier
More and more evidences show that macrophages can induce both pro-tumor and anti-
tumor effects. The study on genetically engineered macrophages to kill tumor cells has …

A novel energy-efficient resource allocation algorithm based on immune clonal optimization for green cloud computing

W Shu, W Wang, Y Wang - EURASIP Journal on Wireless …, 2014 - Springer
Cloud computing is a style of computing in which dynamically scalable and other virtualized
resources are provided as a service over the Internet. The energy consumption and …

α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation

M Pavel, SJ Park, RA Frake, SM Son, MM Manni… - Nature …, 2021 - nature.com
The factors regulating cellular identity are critical for understanding the transition from health
to disease and responses to therapies. Recent literature suggests that autophagy …

The re-polarisation of M2 and M1 macrophages and its role on cancer outcomes

NY den Breems, R Eftimie - Journal of theoretical biology, 2016 - Elsevier
The anti-tumour and pro-tumour roles of Th1/Th2 immune cells and M1/M2 macrophages
have been documented by numerous experimental studies. However, it is still unknown how …

Multiscale coupling of an agent-based model of tissue fibrosis and a logic-based model of intracellular signaling

SM Rikard, TL Athey, AR Nelson… - Frontiers in …, 2019 - frontiersin.org
Wound healing and fibrosis following myocardial infarction (MI) is a dynamic process
involving many cell types, extracellular matrix (ECM), and inflammatory cues. As both …

Resistant and susceptible chicken lines show distinctive responses to Newcastle disease virus infection in the lung transcriptome

MS Deist, RA Gallardo, DA Bunn, JCM Dekkers… - BMC genomics, 2017 - Springer
Background Newcastle disease virus (NDV) is a threat to poultry production worldwide. A
better understanding of mechanisms of resistance and susceptibility to this virus will improve …